Evidence map›Paper›PMID 27489764›Full record

ArticleLeukemia research reports2016

Changing of IKZF1 genotype during Philadelphia-negative precursor-B acute lymphoblastic leukemia progression: a short clinical report.

Volha Vshyukova, Alexander Meleshko, Natalia Mihal, Olga Aleinikova

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Volha VshyukovaBelarusian Research Centre for Pediatric Oncology, Hematology and Immunology, 223053, Republic of Belarus, Minsk region, v. Borovlyani, Frunzenskaya st., 43, Belarus.
Alexander MeleshkoBelarusian Research Centre for Pediatric Oncology, Hematology and Immunology, 223053, Republic of Belarus, Minsk region, v. Borovlyani, Frunzenskaya st., 43, Belarus.
Natalia MihalBelarusian Research Centre for Pediatric Oncology, Hematology and Immunology, 223053, Republic of Belarus, Minsk region, v. Borovlyani, Frunzenskaya st., 43, Belarus.
Olga AleinikovaBelarusian Research Centre for Pediatric Oncology, Hematology and Immunology, 223053, Republic of Belarus, Minsk region, v. Borovlyani, Frunzenskaya st., 43, Belarus.
Belarusian Research Center For Pediatric Oncology and Hematology · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

•The case demonstrated a rare event of clonal heterogeneity by IKZF1 gene status in BCRABL1- ALL.•IKZF1 deletions are secondary events in ALL caused by clonal evolution during the treatment.•It's prognostic significance could be more crucial in BCR-ABL- rather than in BCR-ABL + ALL.•IKZF1 gene alterations may be determined and proved at the genome, expression and protein level.•IKZF1 deletions are suitable for MRD detection but not stable compared to Ig/TCR rearrangement.

Identifiers

PMID27489764
PMCPMC4962816
OpenAlexW2465894969

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.