Evidence map›Paper›PMID 27489747›Full record

ArticleACS macro letters2015

Towards Self-regenerating Antimicrobial Polymer Surfaces.

Franziska Dorner, David Boschert, Alexandra Schneider, Wibke Hartleb, Ali Al-Ahmad, Karen Lienkamp

Abstract read
In one paragraph

Article in ACS macro letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Degradable Polymer Films Made from Poly(salicylic-acid-Macromolecular chemistry and physics · 2020
    Article
  2. Solution-Mediated Modulation ofAntibiotics (Basel, Switzerland) · 2019
    Article
  3. Article
  4. Article
  5. A Degradable and Antimicrobial Surface-attached Polymer HydrogelMacromolecular chemistry and physics · 2018
    Article
  6. Article
  7. Article
  8. Review
  9. Antimicrobial Polymers in the Nano-World.Nanomaterials (Basel, Switzerland) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Franziska DornerDepartment of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany and Freiburg Centre for Interactive Materials and Bioinspired Technologies (FIT) Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
David BoschertDepartment of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany and Freiburg Centre for Interactive Materials and Bioinspired Technologies (FIT) Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
Alexandra SchneiderDepartment of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany and Freiburg Centre for Interactive Materials and Bioinspired Technologies (FIT) Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
Wibke HartlebDepartment of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany and Freiburg Centre for Interactive Materials and Bioinspired Technologies (FIT) Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
Ali Al-AhmadDepartment of Operative Dentistry and Periodontology, Center for Dental Medicine of the Albert-Ludwigs-Universität Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany.
Karen LienkampDepartment of Microsystems Engineering (IMTEK), Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany and Freiburg Centre for Interactive Materials and Bioinspired Technologies (FIT) Albert-Ludwigs-Universität, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.

Funding

European Research Council 637920
6 · The paper itself

Abstract

Regeneration of functional polymer surfaces after damage or contamination is an unresolved scientific challenge, and also of practical importance. In this proof-of-concept study, we present a method to regenerate a functional surface property using a polymer multi-layer architecture. This is exemplified using antimicrobially active surfaces. The idea is to shed the top layer of the polymer layer stack, like a reptile shedding its skin. The proof-of-concept stack consists of two antimicrobial layers and a degradable interlayer. Shedding of the top layer is enabled by degrading that interlayer. The shedding process was analyzed by quantitative fluorescence microscopy, ellipsometry, and FTIR spectroscopy. Antimicrobial assays revealed that the functionality of the emerging antimicrobial layer was fully retained after shedding.

Identifiers

PMID27489747
PMCPMC4968630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.