Evidence map›Paper›PMID 27489569›Full record

ArticleBioData mining2016

Mango: combining and analyzing heterogeneous biological networks.

Jennifer Chang, Hyejin Cho, Hui-Hsien Chou

Abstract read
In one paragraph

Article in BioData mining, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Heterogeneous network approaches to protein pathway prediction.Computational and structural biotechnology journal · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer Chang *Department of Genetics, Development and Cell Biology, Iowa State University, Iowa, 50011 Ames USA.
Hyejin ChoDepartment of Genetics, Development and Cell Biology, Iowa State University, Iowa, 50011 Ames USA.
Hui-Hsien Chou *Department of Genetics, Development and Cell Biology, Iowa State University, Iowa, 50011 Ames USA.ORCID 0000-0002-2029-8743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeterogeneous biological data such as sequence matches, gene expression correlations, protein-protein interactions, and biochemical pathways can be merged and analyzed via graphs, or networks. Existing software for network analysis has limited scalability to large data sets or is only accessible to software developers as libraries. In addition, the polymorphic nature of the data sets requires a more standardized method for integration and exploration.

resultsMango facilitates large network analyses with its Graph Exploration Language, automatic graph attribute handling, and real-time 3-dimensional visualization. On a personal computer Mango can load, merge, and analyze networks with millions of links and can connect to online databases to fetch and merge biological pathways.

conclusionsMango is written in C++ and runs on Mac OS, Windows, and Linux. The stand-alone distributions, including the Graph Exploration Language integrated development environment, are freely available for download from http://www.complex.iastate.edu/download/Mango. The Mango User Guide listing all features can be found at http://www.gitbook.com/book/j23414/mango-user-guide.

Indexed as

3D visualizationBiological pathway analysisGraph mathematicsHeterogeneous data integrationSystems biology

Identifiers

PMID27489569
PMCPMC4971676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.