ArticleMolecular biology of the cell2016
Loss of Gα12/13 exacerbates apical area dependence of actomyosin contractility.
Article in Molecular biology of the cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Apical constriction requires patterned apical surface remodeling to synchronize cellular deformation.eLife · 2025Article
- GPCR-Gα13 Involvement in Mitochondrial Function, Oxidative Stress, and Prostate Cancer.International journal of molecular sciences · 2024Review
- Article
- GαFrontiers in cell and developmental biology · 2022Review
- Mechanical competition alters the cellular interpretation of an endogenous genetic program.The Journal of cell biology · 2021Article
- TheMolecular biology of the cell · 2020Article
- Article
- The Physical Mechanisms ofGenetics · 2020Article
- Structural Redundancy in Supracellular Actomyosin Networks Enables Robust Tissue Folding.Developmental cell · 2019Article
- A Cell-based Assay to Investigate Non-muscle Myosin II Contractility via the Folded-gastrulation Signaling Pathway in Drosophila S2R+ Cells.Journal of visualized experiments : JoVE · 2018Article
- Geometric constraints during epithelial jamming.Nature physics · 2018Article
- Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13-RhoA-ROCK signaling pathway.Experimental & molecular medicine · 2018Article
- Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila.Nature communications · 2017Article
- Actomyosin-based tissue folding requires a multicellular myosin gradient.Development (Cambridge, England) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
During development, coordinated cell shape changes alter tissue shape. In the Drosophila ventral furrow and other epithelia, apical constriction of hundreds of epithelial cells folds the tissue. Genes in the G
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.