ArticleThe Journal of infectious diseases2016
Sequential Acquisition of Anal Human Papillomavirus (HPV) Infection Following Genital Infection Among Men Who Have Sex With Women: The HPV Infection in Men (HIM) Study.
Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- High Risk of Incident-Persistent Human Papillomavirus Infection With 9-Valent Vaccine Types in Young Men With an HPV Infection.Open forum infectious diseases · 2026Article
- Multi-site HPV infection in women with cervical intraepithelial neoplasia: an exploratory analysis.Journal of the Turkish German Gynecological Association · 2025Article
- HPV negative conversion following Hiporfin PDT for HPV associated HSIL in the female lower reproductive tract.Scientific reports · 2025Article
- Sexual risk characteristics, social vulnerability, and anal cancer screening uptake among men living with HIV in the deep south.AIDS care · 2024Article
- Natural History of Anal HPV Infection in Women Treated for Cervical Intraepithelial Neoplasia.Cancers · 2023Article
- Incidence and Clearance of Anal Human Papillomavirus Infection in 16 164 Individuals, According to Human Immunodeficiency Virus Status, Sex, and Male Sexuality: An International Pooled Analysis of 34 Longitudinal Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- The Association between Smoking and Anal Human Papillomavirus in the HPV Infection in Men Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
- Sexual practices and HPV infection in unvaccinated young adults.Scientific reports · 2022Article
- Cervical, oral and anal Human papillomavirus infection in women attending the Dermatology Unit of a regional reference hospital in Genoa, Italy: a prevalence study.Journal of preventive medicine and hygiene · 2022Article
- Sequential acquisition of human papillomavirus infection between genital and oral anatomic sites in males.International journal of cancer · 2021Article
- Concurrent and Concordant Anal and Oral Human PapillomaVirus Infections Are Not Associated with Sexual Behavior in At-Risk Males.Pathogens (Basel, Switzerland) · 2021Article
- Differences in Factors Associated With High- and Low-Risk Oral Human Papillomavirus Genotypes in Men.The Journal of infectious diseases · 2021Article
- Article
- Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China.Emerging infectious diseases · 2020Article
- Cervical, anal and oral HPV detection and HPV type concordance among women referred for colposcopy.Infectious agents and cancer · 2020Article
- Integrating measures of viral prevalence and seroprevalence: a mechanistic modelling approach to explaining cohort patterns of human papillomavirus in women in the USA.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Dynamics and Determinants of HPV Infection: The Michigan HPV and Oropharyngeal Cancer (M-HOC) Study.BMJ open · 2018Article
- Article
- Recurring infection with ecologically distinct HPV types can explain high prevalence and diversity.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Comparison of anal HPV natural history among men by country of residence: Brazil, Mexico, and the United States.The Journal of infection · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundThe purpose of this study was to assess the risk of sequential acquisition of anal human papillomavirus (HPV) infection following a type-specific genital HPV infection for the 9-valent vaccine HPV types and investigate factors associated with sequential infection among men who have sex with women (MSW).
methodsGenital and anal specimens were available for 1348 MSW participants, and HPV genotypes were detected using the Roche Linear Array assay. Sequential risk of anal HPV infection was assessed using hazard ratios (HRs) among men with prior genital infection, compared with men with no prior genital infection, in individual HPV type and grouped HPV analyses.
resultsIn individual analyses, men with prior HPV 16 genital infections had a significantly higher risk of subsequent anal HPV 16 infections (HR, 4.63; 95% confidence interval [CI], 1.41-15.23). In grouped analyses, a significantly higher risk of sequential type-specific anal HPV infections was observed for any of the 9 types (adjusted HR, 2.80; 95% CI, 1.32-5.99), high-risk types (adjusted HR, 2.65; 95% CI, 1.26, 5.55), and low-risk types (adjusted HR, 5.89; 95% CI, 1.29, 27.01).
conclusionsMSW with prior genital HPV infections had a higher risk of a subsequent type-specific anal infection. The higher risk was not explained by sexual intercourse with female partners. Autoinoculation is a possible mechanism for the observed association.
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Registered trials
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