Evidence map›Paper›PMID 27489239›Full record

ArticleGut2017

Dyspepsia and the microbiome: time to focus on the small intestine.

Laurie Zhong, Erin R Shanahan, Ashok Raj, Natasha A Koloski, Linda Fletcher, Mark Morrison, Marjorie M Walker, Nicholas J Talley, Gerald Holtmann

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Gut, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05720793 (A Clinical Trial to Evaluate the Safety and Tolerability of Fecal Microbiota Transplantation in a Population With Obsessive-compulsive Disorder), which is not on this map. Cited by 92 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 2 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05720793 phase2unknown statusnot on this mapstarted 2023, after this paper: background citation

A Clinical Trial to Evaluate the Safety and Tolerability of Fecal Microbiota Transplantation in a Population With Obsessive-compulsive Disorder

TypeinterventionalSponsorValerie TaylorRan2023 to 2024Enrolled20ConditionsObsessive-Compulsive DisorderArmsFMT Capsule + SIMBA Capsule
3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 2 syntheses or guidelines pooled it, 204 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Intervention WithFood science & nutrition · 2026
    Article
  5. Critical Review: The Past, Present, and Future of Small Intestinal Bacterial Overgrowth (SIBO).JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  6. Article
  7. Review
  8. Duodenal microbiota profiling and its effects on gastrointestinal tract dysfunction.Frontiers in cellular and infection microbiology · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Clinical Relevance of Gastric Emptying Time in Functional Dyspepsia.Journal of neurogastroenterology and motility · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. The Duodenal Microenvironment in Functional Dyspepsia.Journal of neurogastroenterology and motility · 2025
    Review
  17. Review
  18. Approach to Meal-Related Nausea and Vomiting.Gastroenterology & hepatology · 2025
    Article
  19. Review
  20. [The Relationship of Dysbiosis of Duodenal Microbiome and Functional Dyspepsia].The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Laurie ZhongSchool of Population Health, University of Queensland, Brisbane, Queensland, Australia.
Erin R ShanahanDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland, Australia.
Ashok RajDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland, Australia.
Natasha A KoloskiDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland, Australia.
Linda FletcherDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland, Australia.
Mark MorrisonMicrobial Biology and Metagenomics Research Group, Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.
Marjorie M WalkerFaculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.
Nicholas J TalleyFaculty of Health and Medicine, University of Newcastle, Newcastle, New South Wales, Australia.
Gerald HoltmannDepartment of Gastroenterology and Hepatology, Princess Alexandra Hospital, Translational Research Institute, Woolloongabba, Queensland, Australia.
The University of Queensland · AUPrincess Alexandra Hospital · AUUniversity of Newcastle Australia · AUDiamant (Germany) · DETranslational Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DyspepsiaIntestine, SmallHelicobacter InfectionsHumansMicrobiotaProton Pump InhibitorsProton Pump InhibitorsDUODENAL MUCOSAFUNCTIONAL DYSPEPSIAINTESTINAL MICROBIOLOGYPROTON PUMP INHIBITION

Identifiers

PMID27489239
OpenAlexW2497884722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.