Evidence map›Paper›PMID 27489178›Full record

Trial reportCephalalgia : an international journal of headache2017

Acute migraine medication adherence, migraine disability and patient satisfaction: A naturalistic daily diary study.

Elizabeth K Seng, Matthew S Robbins, Robert A Nicholson

Abstract readPragmatic Clinical Trial
In one paragraph

Trial report in Cephalalgia : an international journal of headache, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Medical Cannabis for Headache Pain: a Primer for Clinicians.Current pain and headache reports · 2021
    Review
  8. Article
  9. Article
  10. Epidemiology and management of medication-overuse headache in the general population.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth K Seng1 Ferkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Matthew S Robbins2 Saul R Korey Department of Neurology, Albert Einstein College of Medicine Bronx, NY, USA.
Robert A Nicholson4 Mercy Virtual, Chesterfield, MO, USA.

Funding

Clinical Decision Support for Patient Migraine ManagementK23NS096107 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SENG-TAMACCIO, ELIZABETH K · 2016 to 2020
$965k
Tailored Messaging and Behavioral Treatment for MigraineK23NS048288 · NINDS · SAINT LOUIS UNIVERSITY · PI NICHOLSON, ROBERT A · 2006 to 2010
$786k
NINDS NIH HHS K23 NS048288NINDS NIH HHS K23 NS096107
6 · The paper itself

Abstract

Objective To examine the influence of acute migraine medication adherence on migraine disability and acute medication satisfaction. Methods Adults with migraine completed three months of daily electronic diaries assessing headache symptoms, acute medication taken, acute medication satisfaction, and daily migraine disability. Repeated measures mixed-effects models examined the effect of initial medication type [migraine-specific medication (MSM) vs. over-the-counter analgesic (OTC) vs. an opiate/barbiturate], the severity of pain at dosing, and their interaction with daily migraine disability and satisfaction with acute medication. Results Participants (N = 337; 92.5% female; 91.1% Caucasian, non-Hispanic; 84.0% with episodic migraine) recorded 29,722 diary days. Participants took acute medication on 96.5% of 8090 migraine days. MSM was most frequently taken first (58%), followed by OTC (29.9%) and an opiate/barbiturate (12.1%). Acute medication was most frequently taken when pain was mild (41.2%), followed by moderate (37.7%) and severe pain (11.4%). Initially dosing with MSM while pain was mild was associated with the lowest daily disability [medication × pain at dosing F (4, 6336.12) = 58.73, p < .001] and highest acute medication satisfaction [medication × pain at dosing F (4, 3867.36) = 24.00, p < .001]. Conclusion Using an MSM (triptan or ergot) first was associated with the lowest migraine disability and highest acute medication satisfaction.

Indexed as

Disability EvaluationMedical RecordsPatient SatisfactionAdultAnalgesics, OpioidFemaleHumansMaleMedication AdherenceMiddle AgedMigraine DisordersNonprescription DrugsSumatriptanAnalgesics, OpioidNonprescription DrugsSumatriptanacute drug therapyadherencedisabilityMigrainepatient satisfaction

Identifiers

PMID27489178
PMCPMC5329165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.