ArticleLangenbeck's archives of surgery2017
Postoperative ileus: in search of an international consensus on definition, diagnosis, and treatment.
Article in Langenbeck's archives of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04001985 (Nasogastric Tube Clamping Trial), which is not on this map. Cited by 50 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nasogastric Tube Clamping Trial: Is it Useful? A Proposed Algorithm for Removal.
Who cites it
50 citing papers in PubMed, 7 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Effectiveness of comprehensive interventions including exercise and exercise-only interventions on postoperative ileus and recovery of intestinal function in patients with colorectal cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Effect of postoperative coffee consumption on gastrointestinal function after cesarean section, a systematic review and meta-analysis of randomized controlled trials.BMC public health · 2026Pooled it
- The impact of gum-chewing on postoperative ileus following gynecological cancer surgery: A systematic review and meta-analysis of randomized controlled trials.Frontiers in oncology · 2022Pooled it
- Effect of Postoperative Coffee Consumption on Postoperative Ileus after Abdominal Surgery: An Updated Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Comparison of treatment to improve gastrointestinal functions after colorectal surgery within enhanced recovery programmes: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- The Impact of Sham Feeding with Chewing Gum on Postoperative Ileus Following Colorectal Surgery: a Meta-Analysis of Randomised Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Pooled it
- Systematic review of definitions and outcome measures for return of bowel function after gastrointestinal surgery.BJS open · 2019Pooled it
- Evaluation of TU-100 (Daikenchuto), a Traditional Japanese Kampo Medicine, as an Adjunct to Enhanced Recovery After Surgery, for Acceleration of Gastrointestinal Recovery After Bowel Resection: Results of a Proof-of-Concept, Phase 2, Randomized, Double-Blinded, Placebo-Controlled Trial.Diseases of the colon and rectum · 2026Trial
- The effects of fentanyl, oxycodone, and butorphanol on gastrointestinal function in patients undergoing laparoscopic hysterectomy: a prospective, double-blind, randomized controlled trial.BMC anesthesiology · 2022Trial
- Effect of transcutaneous vagus nerve stimulation on muscle activity in the gastrointestinal tract (transVaGa): a prospective clinical trial.International journal of colorectal disease · 2019Trial
- Program of gastrointestinal rehabilitation and early postoperative enteral nutrition: a prospective study.Updates in surgery · 2018Trial
- Nicotine chewing gum for the prevention of postoperative ileus after colorectal surgery: a multicenter, double-blind, randomised, controlled pilot study.International journal of colorectal disease · 2017Trial
- Beyond total operative time: phase-specific robotic efficiency and postoperative morbidity following colorectal resection - a multisurgeon cohort study.Journal of robotic surgery · 2026Article
- A Randomized Controlled Trial of Paula Method Versus Gum Chewing for Gastrointestinal Reactivation After Cesarean Delivery.Journal of clinical medicine · 2026Article
- Investigation of the improvement effect of Dajianzhong decoction on rats with post-operative ileus based on serum metabolomics and spectrum-effect relationship.Frontiers in pharmacology · 2026Article
- A predictive tool for postoperative ileus after ileostomy closure: Model development and validation.Turkish journal of surgery · 2025Article
- Postoperative ileus after emergency surgery for acute bowel obstruction: a case-control study of predictors and impact on recovery.Langenbeck's archives of surgery · 2025Article
- Incidence and clinical predictors of postoperative ileus following non-abdominal surgery in Ethiopia: a prospective cohort study.Langenbeck's archives of surgery · 2025Article
- The role of medium-frequency pulsed electrotherapy in patients with postoperative ileus after gynecological surgery.Frontiers in surgery · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative ileus (POI) is a frequent complication after abdominal surgery; nonetheless, it remains poorly defined. Our aim was to achieve an international consensus among leading colorectal surgeons on definition, prevention, and treatment of POI.
methodsThirty-five experts from five continents participated in a three-round Delphi process. Round 1 contained open-ended questions on POI and postoperative nausea and vomiting (PONV). Round 2 included closed-ended questions. Round 3 measured agreement on a 5-point Likert scale. Consensus was defined when items were rated as agree or strongly agree by at least 70 % of the experts.
resultsExperts reached following consensus: POI is a temporary inhibition (86 %) of gastrointestinal motility after surgical intervention due to non-mechanical causes (89 %) and prevents sufficient oral intake (96 %). Abdominal distension/tenderness are the most relevant clinical signs (71 %). Nasogastric tube placement is not mandatory (78 %) but can be removed without previous clamping (81 %)/gastrointestinal contrast study (100 %). Preventive measures are recommended to decrease the risk of POI (96 %): narcotic sparing analgesia (89 %) and fluid optimization (74 %). Treatment of POI should include stimulation of ambulation (96 %) and stop of opioids (74 %). Total parenteral nutrition is recommended from the 7th day without sufficient oral intake (81 %). There was no consensus on the ranking of POI's symptoms, on the imaging modality of choice for the diagnosis of POI, neither on the difference between POI and PONV.
conclusionsThis Delphi study achieved consensus on the definition, relevant clinical signs, prevention, treatment, and supportive care of POI. Areas of non-consensus were identified (necessity and modality of radiologic imaging to establish the diagnosis, difference between POI and PONV), giving opportunity for further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.