Evidence map›Paper›PMID 27488865›Full record

ArticleJournal of natural medicines2017

Green tea cultivar 'Benifuuki' potentiates split vaccine-induced immunoglobulin A production.

Yeong-Seon Won, Motofumi Kumazoe, Kanako Takamatsu, Yuki Shinoda, Saki Sonoda, Kenji Okada, Takehisa Okamoto, Hirofumi Tachibana

Abstract read
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In one paragraph

Article in Journal of natural medicines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yeong-Seon WonDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, Japan.
Motofumi KumazoeDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, Japan.
Kanako TakamatsuDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, Japan.
Yuki ShinodaProducts Research and Development Laboratory, Asahi Soft Drinks Co., Ltd., Ibaraki, 302-0106, Japan.
Saki SonodaProducts Research and Development Laboratory, Asahi Soft Drinks Co., Ltd., Ibaraki, 302-0106, Japan.
Kenji OkadaProducts Research and Development Laboratory, Asahi Soft Drinks Co., Ltd., Ibaraki, 302-0106, Japan.
Takehisa OkamotoProducts Research and Development Laboratory, Asahi Soft Drinks Co., Ltd., Ibaraki, 302-0106, Japan.
Hirofumi TachibanaDivision of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, Japan. tatibana@agr.kyushu-u.ac.jp.
Asahi Breweries (Japan) · JPKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza is a widespread disease caused by infection with the influenza virus. Vaccination is considered to be the main countermeasure against influenza. A split vaccine is widely used to avoid severe adverse events, and it induces strong humoral immunity. However, the split vaccine alone cannot elicit mucosal immunity, including IgA production, and its preventative effects are limited. Here, we show that the green tea cultivar 'Benifuuki' extract enhanced the effect of a split vaccine on mucosal immunity. The frequency of IgA

Indexed as

AnimalsFemaleImmunoglobulin AInfluenza VaccinesMiceMice, Inbred BALB CModels, AnimalPlant ExtractsTeaImmunoglobulin AInfluenza VaccinesPlant ExtractsTeaBenifuukiGreen teaInfluenza virusMethylated EGCGSplit vaccineVirus-specific IgA

Identifiers

PMID27488865
OpenAlexW2488635380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.