ArticleAlcoholism, clinical and experimental research2016
Emergency Department Visits for Adverse Drug Reactions Involving Alcohol: United States, 2005 to 2011.
Article in Alcoholism, clinical and experimental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 41 citations in OpenAlex.
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- Drug interactions in patients with alcohol use disorder: results from a real-world study on an addiction-specific ward.Therapeutic advances in drug safety · 2025Article
- Influence of inpatient withdrawal treatment on drug safety in alcohol use disorder - a quasi-experimental pre-post study.BMC psychiatry · 2024Article
- Clinical characteristics and risk factors analysis of 505 cases of infusion reactions in a tertiary hospital.Frontiers in pharmacology · 2024Article
- Incidence, Timing and Social Correlates of the Development of Opioid Use Disorder Among Clients Seeking Treatment for an Alcohol Use Problem: Changes Over the Three Waves of the Opioid Epidemic.Substance abuse and rehabilitation · 2024Article
- Determinants of long-term opioid prescribing in an urban population: A cross-sectional study.British journal of clinical pharmacology · 2022Article
- Co-use of medication and alcohol: The influence on subjective effects of intoxication and affect.Personality disorders · 2022Article
- Understanding differences in prescription drug misuse between two Texas border communities.Ethnicity & health · 2021Article
- Nonmedical Prescription Opioid Use among a Sample of College Students: Prevalence and Predictors.Pharmacy (Basel, Switzerland) · 2021Article
- Association of Opioid Use Disorder Treatment With Alcohol-Related Acute Events.JAMA network open · 2021Article
- The changing landscape of alcohol use disorder and problem drinking in the USA: implications for primary care.Family practice · 2020Article
- Trends in Binge and Heavy Drinking among Adults in the United States, 2011-2017.Substance use & misuse · 2020Article
- The Role of Drugs in Alcohol Poisoning and Blackout Events: A Latent Class Analysis of a Residential Treatment Sample.Alcoholism, clinical and experimental research · 2019Article
- Positive drug test trends in fatally-injured drivers in the United States from 2007 to 2017.Substance abuse treatment, prevention, and policy · 2019Article
- Trends in Prescribed Central Nervous System Depressant Medications Among Adults Who Regularly Consume Alcohol: United States 1999 to 2014.Alcoholism, clinical and experimental research · 2019Article
- Immediate effects of a brief intervention to prevent alcohol and medication interactions among older adults.Health education research · 2018Article
- Alcohol and Opioid Use, Co-Use, and Chronic Pain in the Context of the Opioid Epidemic: A Critical Review.Alcoholism, clinical and experimental research · 2018Review
- Sustained Intervention Effects on Older Adults' Attitudes Towards Alcohol and Medication Interactions.American journal of health education · 2018Article
- Article
- Trends in Alcohol Consumption Among Older Americans: National Health Interview Surveys, 1997 to 2014.Alcoholism, clinical and experimental research · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlcohol consumption may interfere with absorption, distribution, metabolism, and excretion of medications and increase risk of adverse drug reactions (ADR). Studies report increasing prescription medication use over time, with many U.S. drinkers using alcohol-interactive medication. This study identified trends in incidence of U.S. emergency department (ED) visits for ADR with alcohol involvement (ADR-A), compared characteristics and disposition between ADR-A visits and ADR visits without alcohol involvement (ADR-NA), and examined frequency of implicated medications in such visits for 2005 to 2011.
methodsADR visits were identified through the Drug Abuse Warning Network, a national surveillance system monitoring drug-related ED visits. Analysis accounted for sampling design effects and sampling weights. Estimates are presented for totals (ages 12+), age group, and/or sex. Trends were assessed by joinpoint log-linear regression. Differences between ADR-A and ADR-NA visits were compared using two-tailed Rao-Scott chi-square tests.
resultsFrom 2005 to 2011, incidence of ADR-A visits increased for males and females ages 21 to 34 and females ages 55+. An average of 25,303 ADR-A visits ages 12+ occurred annually. Compared with ADR-NA visits, ADR-A visits were more likely to involve males, patients ages 21 to 54, and 2+ implicated drugs. Alcohol involvement increased odds of more serious outcomes from ADR visits. Central nervous system (CNS) agents were the most common medications in ADR-A visits (59.1%), with nearly half being analgesics (mainly opioid). About 13.8% of ADR-A visits involved psychotherapeutic agents, including antidepressants. Besides CNS and psychotherapeutic agents, ADR-A visits involved a higher percentage of genitourinary-tract agents (mainly for impotence) than ADR-NA visits. Sex and age variations were observed with certain implicated medications.
conclusionsED visits for alcohol-drug interactions can be prevented by avoiding alcohol when taking alcohol-interactive medications. Our results underscore the need for healthcare professionals to routinely ask patients about alcohol consumption and warn of ADR risks before prescribing and dispensing alcohol-interactive medications.
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