Evidence map›Paper›PMID 27488128›Full record

ReviewSports health2016

MR Parametric Mapping as a Biomarker of Early Joint Degeneration.

Eric Y Chang, Yajun Ma, Jiang Du

Open access · greenAbstract readReview
In one paragraph

Review in Sports health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Correlation between the elastic modulus of anterior cruciate ligament (ACL) and quantitative ultrashort echo time (UTE) magnetic resonance imaging.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  5. Article
  6. Ultrashort echo time adiabatic TMagnetic resonance imaging · 2021
    Article
  7. Article
  8. Article
  9. Quantitative MRI Musculoskeletal Techniques: An Update.AJR. American journal of roentgenology · 2019
    Review
  10. Article
  11. Article
  12. Principal component analysis-TQuantitative imaging in medicine and surgery · 2016
    Article
  13. Emerging Technologies.Sports health · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eric Y ChangRadiology Service, VA San Diego Healthcare System, San Diego, California Department of Radiology, University of California, San Diego Medical Center, San Diego, California ericchangmd@gmail.com.
Yajun MaDepartment of Radiology, University of California, San Diego Medical Center, San Diego, California.
Jiang DuDepartment of Radiology, University of California, San Diego Medical Center, San Diego, California.
University of California San Diego Medical Center · US

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
Non-invasive Morphologic and Biochemical Assessment of Tendon with Novel UTE-MRIIK2CX000749 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2012 to 2015
–
CSRD VA I01 CX001388CSRD VA IK2 CX000749NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987
6 · The paper itself

Abstract

contextOsteoarthritis (OA) is a common, worldwide disorder. Magnetic resonance (MR) imaging can directly and noninvasively evaluate articular cartilage and has emerged as an essential tool in the study of OA. EVIDENCE ACQUISITION: A PubMed search was performed using the keywords quantitative MRI and cartilage. No limits were set on the range of years searched. Articles were reviewed for relevance with an emphasis on in vivo studies performed at 3 tesla. STUDY

designClinical review. LEVEL OF EVIDENCE: Level 4.

resultsT2, T2*, T1 (particularly when measured after exogenous contrast administration, such as with the delayed gadolinium-enhanced MR imaging of cartilage [dGEMRIC] technique), and T1ρ are among the most widely utilized quantitative MR imaging techniques to evaluate cartilage and have been implemented in various patient cohorts. Existing challenges include reproducibility of results, insufficient consensus regarding optimal sequences and parameters, and interpretation of values.

conclusionQuantitative assessment of cartilage using MR imaging techniques likely represents the best opportunity to identify early cartilage degeneration and to follow patients after treatment. Despite existing challenges, ongoing work and unique approaches have shown exciting and promising results.

Indexed as

Magnetic Resonance ImagingCartilage, ArticularCollagenHumansOsteoarthritisOsteoarthritis, KneeProteoglycansReproducibility of ResultsCollagenProteoglycanscartilageosteoarthritisparametric mappingquantitative MRI

Identifiers

PMID27488128
PMCPMC5010134
OpenAlexW2498196739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.