Evidence map›Paper›PMID 27488023›Full record

ArticleGene therapy2016

Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study.

R Kaminski, R Bella, C Yin, J Otte, P Ferrante, H E Gendelman, H Li, R Booze, J Gordon, W Hu and 1 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Gene therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Molecular therapy. Nucleic acids · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Genome editing methods in animal models.Animal cells and systems · 2020
    Review
  11. Article
  12. CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1.Frontiers in cellular and infection microbiology · 2020
    Review
  13. A Broad Application of CRISPR Cas9 in Infectious Diseases of Central Nervous System.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2019
    Review
  14. Review
  15. Article
  16. Barriers for HIV Cure: The Latent Reservoir.AIDS research and human retroviruses · 2018
    Review
  17. Review
  18. Review
  19. Article
  20. Novel AIDS therapies based on gene editing.Cellular and molecular life sciences : CMLS · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

R Kaminski
R Bella
C Yin
J Otte
P Ferrante
H E Gendelman
H Li
R Booze
J Gordon
W Hu
K Khalili

Funding

Viral Gene Editing and Bioinformatics Core for Institution # 269291P30MH092177 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI Ilker Kudret Sariyer · 2011 to 2026
$24.9M
NIMH NIH HHS P30 MH092177
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID27488023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.