ArticleScientific reports2016
Thermal fluctuations affect the transcriptome through mechanisms independent of average temperature.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 70 citations in OpenAlex.
- Two Secondary Introductions From a Shared Bridgehead Population Show Evidence of Divergent and Parallel Selection.Molecular ecology · 2026Article
- Enhancement of heat resistance ofEngineering microbiology · 2026Article
- Integrated mRNA and miRNA Omics Analyses Reveal Transcriptional Regulation of the Tolerance Traits byInsects · 2025Article
- Thermal variation influences the transcriptome of the major malaria vector Anopheles stephensi.Communications biology · 2025Article
- Diapause-Linked Gene Expression Pattern and Related Candidate Duplicated Genes of the Mountain ButterflyInternational journal of molecular sciences · 2023Article
- Signaling through the dystrophin glycoprotein complex affects the stress-dependent transcriptome in Drosophila.Disease models & mechanisms · 2023Article
- The effect of a temperature-sensitive prophage on the evolution of virulence in an opportunistic bacterial pathogen.Molecular ecology · 2022Article
- Molecular mechanisms underlying plasticity in a thermally varying environment.Molecular ecology · 2022Article
- Wide Diurnal Temperature Amplitude and High Population Density Can Positively Affect the Life History of Sitobion avenae (Hemiptera: Aphididae).Journal of insect science (Online) · 2021Article
- Rapid within- and transgenerational changes in thermal tolerance and fitness in variable thermal landscapes.Ecology and evolution · 2020Article
- Pronounced Plastic and Evolutionary Responses to Unpredictable Thermal Fluctuations inFrontiers in genetics · 2020Article
- Review
- Integrating GWAS and Transcriptomics to Identify the Molecular Underpinnings of Thermal Stress Responses inFrontiers in genetics · 2020Article
- Evolution and Plasticity of the Transcriptome Under Temperature Fluctuations in the Fungal Plant PathogenFrontiers in microbiology · 2020Article
- Article
- Genetic Constraints, Transcriptome Plasticity, and the Evolutionary Response to Climate Change.Frontiers in genetics · 2020Article
- Independent and combined effects of daytime heat stress and night-time recovery determine thermal performance.Biology open · 2019Article
- Trait variation in extreme thermal environments under constant and fluctuating temperatures.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Effects of adult temperature on gene expression in a butterfly: identifying pathways associated with thermal acclimation.BMC evolutionary biology · 2019Article
- Comparative studies of critical physiological limits and vulnerability to environmental extremes in small ectotherms: How much environmental control is needed?Integrative zoology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Terrestrial ectotherms are challenged by variation in both mean and variance of temperature. Phenotypic plasticity (thermal acclimation) might mitigate adverse effects, however, we lack a fundamental understanding of the molecular mechanisms of thermal acclimation and how they are affected by fluctuating temperature. Here we investigated the effect of thermal acclimation in Drosophila melanogaster on critical thermal maxima (CTmax) and associated global gene expression profiles as induced by two constant and two ecologically relevant (non-stressful) diurnally fluctuating temperature regimes. Both mean and fluctuation of temperature contributed to thermal acclimation and affected the transcriptome. The transcriptomic response to mean temperatures comprised modification of a major part of the transcriptome, while the response to fluctuations affected a much smaller set of genes, which was highly independent of both the response to a change in mean temperature and to the classic heat shock response. Although the independent transcriptional effects caused by fluctuations were relatively small, they are likely to contribute to our understanding of thermal adaptation. We provide evidence that environmental sensing, particularly phototransduction, is a central mechanism underlying the regulation of thermal acclimation to fluctuating temperatures. Thus, genes and pathways involved in phototransduction are likely of importance in fluctuating climates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.