ArticleMedical physics2016
Technical Note: A treatment plan comparison between dynamic collimation and a fixed aperture during spot scanning proton therapy for brain treatment.
Article in Medical physics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Use of apertures in single-energy pristine Bragg peak FLASH radiotherapy.Journal of applied clinical medical physics · 2026Article
- Enhancing dose conformity in head and neck intensity-modulated proton therapy using a novel dynamic multi-leaf collimator strategy.Medical physics · 2026Article
- Range-compensated pencil beam scanning proton Arc therapy: a feasibility study.Communications engineering · 2025Article
- The LET enhancement of energy-specific collimation in pencil beam scanning proton therapy.Journal of applied clinical medical physics · 2025Article
- Patient-specific quality assurance of dynamically-collimated proton therapy treatment plans.Medical physics · 2024Article
- PETRA: A pencil beam trimming algorithm for analytical proton therapy dose calculations with the dynamic collimation system.Medical physics · 2023Article
- Integration and dosimetric validation of a dynamic collimation system for pencil beam scanning proton therapy.Biomedical physics & engineering express · 2023Article
- A novel optimization algorithm for enabling dynamically collimated proton arc therapy.Scientific reports · 2022Article
- Validation of pencil beam scanning proton therapy with multi-leaf collimator calculated by a commercial Monte Carlo dose engine.Journal of applied clinical medical physics · 2022Article
- The dosimetric enhancement of GRID profiles using an external collimator in pencil beam scanning proton therapy.Medical physics · 2022Article
- A scoping review of patient selection methods for proton therapy.Journal of medical radiation sciences · 2022Article
- Investigating aperture-based approximations to model a focused dynamic collimation system for pencil beam scanning proton therapy.Biomedical physics & engineering express · 2022Article
- Proton therapy needs further technological development to fulfill the promise of becoming a superior treatment modality (compared to photon therapy).Journal of applied clinical medical physics · 2021Article
- Dose distribution effects of spot-scanning proton beam therapy equipped with a multi-leaf collimator for pediatric brain tumors.Oncology letters · 2021Article
- Development and validation of the Dynamic Collimation Monte Carlo simulation package for pencil beam scanning proton therapy.Medical physics · 2021Article
- Innovations and the Use of Collimators in the Delivery of Pencil Beam Scanning Proton Therapy.International journal of particle therapy · 2021Article
- Clinical Implementation of Proton Therapy Using Pencil-Beam Scanning Delivery Combined With Static Apertures.Frontiers in oncology · 2021Article
- Experimental and Monte Carlo characterization of a dynamic collimation system prototype for pencil beam scanning proton therapy.Medical physics · 2020Article
- An investigation into the robustness of dynamically collimated proton therapy treatments.Medical physics · 2020Article
- Neutron dose and its measurement in proton therapy-current State of Knowledge.The British journal of radiology · 2020Review
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo quantitatively assess the advantages of energy-layer specific dynamic collimation system (DCS) versus a per-field fixed aperture for spot scanning proton therapy (SSPT).
methodsFive brain cancer patients previously planned and treated with SSPT were replanned using an in-house treatment planning system capable of modeling collimated and uncollimated proton beamlets. The uncollimated plans, which served as a baseline for comparison, reproduced the target coverage and organ-at-risk sparing of the clinically delivered plans. The collimator opening for the fixed aperture-based plans was determined from the combined cross sections of the target in the beam's eye view over all energy layers which included an additional margin equivalent to the maximum beamlet displacement for the respective energy of that energy layer. The DCS-based plans were created by selecting appropriate collimator positions for each row of beam spots during a Raster-style scanning pattern which were optimized to maximize the dose contributions to the target and limited the dose delivered to adjacent normal tissue.
resultsThe reduction of mean dose to normal tissue adjacent to the target, as defined by a 10 mm ring surrounding the target, averaged 13.65% (range: 11.8%-16.9%) and 5.18% (2.9%-7.1%) for the DCS and fixed aperture plans, respectively. The conformity index, as defined by the ratio of the volume of the 50% isodose line to the target volume, yielded an average improvement of 21.35% (19.4%-22.6%) and 8.38% (4.7%-12.0%) for the DCS and fixed aperture plans, respectively.
conclusionsThe ability of the DCS to provide collimation to each energy layer yielded better conformity in comparison to fixed aperture plans.
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