Evidence map›Paper›PMID 27487878›Full record

ArticleMedical physics2016

Multisource inverse-geometry CT. Part II. X-ray source design and prototype.

V Bogdan Neculaes, Antonio Caiafa, Yang Cao, Bruno De Man, Peter M Edic, Kristopher Frutschy, Satish Gunturi, Lou Inzinna, Joseph Reynolds, Mark Vermilyea and 5 more

Abstract readValidation Study
In one paragraph

Article in Medical physics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

V Bogdan NeculaesGE Global Research, Niskayuna, New York 12309.
Antonio CaiafaGE Global Research, Niskayuna, New York 12309.
Yang CaoGE Global Research, Niskayuna, New York 12309.
Bruno De ManGE Global Research, Niskayuna, New York 12309.
Peter M EdicGE Global Research, Niskayuna, New York 12309.
Kristopher FrutschyGE Global Research, Niskayuna, New York 12309.
Satish GunturiGE Global Research, Niskayuna, New York 12309.
Lou InzinnaGE Global Research, Niskayuna, New York 12309.
Joseph ReynoldsGE Global Research, Niskayuna, New York 12309.
Mark VermilyeaGE Global Research, Niskayuna, New York 12309.
David WagnerGE Global Research, Niskayuna, New York 12309.
Xi ZhangGE Global Research, Niskayuna, New York 12309.
Yun ZouGE Global Research, Niskayuna, New York 12309.
Norbert J PelcDepartment of Radiology, Stanford University, Stanford, California 94305.
Brian LounsberryHealthcare Science Technology, GE Healthcare, West Milwaukee, Wisconsin 53219.
GE Global Research (United States) · USStanford University · US

Funding

Inverse Geometry CT for Dose-efficient Volumetric ImagingR01EB006837 · NIBIB · STANFORD UNIVERSITY · PI PELC, NORBERT J. · 2006 to 2009
$4.3M
NIBIB NIH HHS R01 EB006837
6 · The paper itself

Abstract

purposeThis paper summarizes the development of a high-power distributed x-ray source, or "multisource," designed for inverse-geometry computed tomography (CT) applications [see B. De Man et al., "Multisource inverse-geometry CT. Part I. System concept and development," Med. Phys. 43, 4607-4616 (2016)]. The paper presents the evolution of the source architecture, component design (anode, emitter, beam optics, control electronics, high voltage insulator), and experimental validation.

methodsDispenser cathode emitters were chosen as electron sources. A modular design was adopted, with eight electron emitters (two rows of four emitters) per module, wherein tungsten targets were brazed onto copper anode blocks-one anode block per module. A specialized ceramic connector provided high voltage standoff capability and cooling oil flow to the anode. A matrix topology and low-noise electronic controls provided switching of the emitters.

resultsFour modules (32 x-ray sources in two rows of 16) have been successfully integrated into a single vacuum vessel and operated on an inverse-geometry computed tomography system. Dispenser cathodes provided high beam current (>1000 mA) in pulse mode, and the electrostatic lenses focused the current beam to a small optical focal spot size (0.5 × 1.4 mm). Controlled emitter grid voltage allowed the beam current to be varied for each source, providing the ability to modulate beam current across the fan of the x-ray beam, denoted as a virtual bowtie filter. The custom designed controls achieved x-ray source switching in <1 μs. The cathode-grounded source was operated successfully up to 120 kV.

conclusionsA high-power, distributed x-ray source for inverse-geometry CT applications was successfully designed, fabricated, and operated. Future embodiments may increase the number of spots and utilize fast read out detectors to increase the x-ray flux magnitude further, while still staying within the stationary target inherent thermal limitations.

Indexed as

CopperElectrodesElectronsEquipment DesignStatic ElectricityTomography Scanners, X-Ray ComputedTomography, X-Ray ComputedTungstenVacuumX-RaysCopperTungsten

Identifiers

PMID27487878
PMCPMC4958104
OpenAlexW2493829474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.