ArticleScientific reports2016
Combined effects of cadmium and salinity on juvenile Takifugu obscurus: cadmium moderates salinity tolerance; salinity decreases the toxicity of cadmium.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 44 citations in OpenAlex.
- Effect of Acute Cadmium Exposure and Short-Term Depuration on Oxidative Stress and Immune Responses inToxics · 2025Article
- Microbial Diversity Affects the Cold Tolerance of Red Swamp Crayfish (Procambarus clarkii) by Regulating Histamine Metabolism.Microbial ecology · 2025Article
- Effect of Different Salinities on the Biochemical Properties and Meat Quality of Adult Freshwater Drum (Antioxidants (Basel, Switzerland) · 2024Article
- Oxidative Stress and Neurotoxicity of Cadmium and Zinc on Artemia franciscana.Biological trace element research · 2023Article
- Molecular Cloning and Functional Characterization of Catalase in Stress Physiology, Innate Immunity, Testicular Development, Metamorphosis, and Cryopreserved Sperm of Pacific Abalone.Antioxidants (Basel, Switzerland) · 2023Article
- Heavy Metals in the Blood Serum and Feces of Mugger Crocodile (Crocodylus palustris) in Sistan and Baluchistan Province, Iran.Biological trace element research · 2022Article
- Effects of Sudden Drop in Salinity on Osmotic Pressure Regulation and Antioxidant Defense Mechanism ofFrontiers in physiology · 2020Article
- Effects of a Sudden Drop in Salinity on Immune Response Mechanisms ofInternational journal of molecular sciences · 2019Article
- Comparative and Interactive Biochemical Effects of Sub-Lethal Concentrations of Cadmium and Lead on Some Tissues of the African Catfish (Toxicological research · 2019Article
- Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.Fish physiology and biochemistry · 2019Article
- Interactive effects of temperature and salinity on the survival, oxidative stress, and NaFish physiology and biochemistry · 2019Article
- Ecotoxicological impact assessment of the brine discharges from a desalination plant in the marine waters of the Algerian west coast, using a multibiomarker approach in a limpet, Patella rustica.Environmental science and pollution research international · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obscure puffer Takifugu obscurus, a species of anadromous fish, experiences several salinity changes in its lifetime. Cadmium (Cd) is a toxic heavy metal that can potentially induce oxidative stress in fish. The present study aimed to detect the combined effects of Cd (0, 5, 10, 20 and 50 mg L(-1)) and salinity (0, 15 and 30 ppt) on juvenile T. obscurus. Results showed the juveniles could survive well under different salinities; however, with Cd exposure, the survival rates significantly decreased at 0 and 30 ppt. At 15 ppt, tolerance to Cd increased. Cd exposure clearly induced oxidative stress, and the responses among different tissues were qualitatively similar. Salinity acted as a protective factor which could reduce the reactive oxygen species and malondialdehyde levels. In addition, salinity could enhance the antioxidant defense system, including superoxide dismutase, catalase and glutathione. Na(+)/K(+)-ATPase activity significantly decreased under Cd exposure in gill, kidney and intestine. These findings indicated that Cd could moderate the adaptability of juvenile T. obscurus to high salinity and low salinity played a protective role upon Cd exposure. Thus, the role of salinity should be considered when evaluating the effect of heavy metals on anadromous and estuarine fishes.
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