Evidence map›Paper›PMID 27487573›Full record

Trial reportJAMA psychiatry2016

Comparative Effectiveness of Cognitive Therapy and Dynamic Psychotherapy for Major Depressive Disorder in a Community Mental Health Setting: A Randomized Clinical Noninferiority Trial.

Mary Beth Connolly Gibbons, Robert Gallop, Donald Thompson, Debra Luther, Katherine Crits-Christoph, Julie Jacobs, Seohyun Yin, Paul Crits-Christoph

Erratum issued Registry-linked trialOpen access · bronzeAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in JAMA psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT01207271 (A Comparison of Cognitive and Dynamic Therapy for MDD in Community Settings), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01207271 nacompletednot on this map

A Comparison of Cognitive and Dynamic Therapy for MDD in Community Settings

TypeinterventionalSponsorUniversity of PennsylvaniaRan2010 to 2014Enrolled237ConditionsMajor Depressive DisorderArmsCognitive Therapy, Supportive-Expressive Psychodynamic Therapy
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 95 citations in OpenAlex.

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  19. Instrumental variable analyses for causal inference: Application to multilevel analyses of the alliance-outcome relation.Psychotherapy research : journal of the Society for Psychotherapy Research · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mary Beth Connolly GibbonsDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Robert GallopDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Donald ThompsonNHS Human Services, Erdenheim, Pennsylvania.
Debra LutherNHS Human Services, Erdenheim, Pennsylvania.
Katherine Crits-ChristophDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Julie JacobsDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Seohyun YinDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Paul Crits-ChristophDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
University of Pennsylvania · USPennsylvania Department of Human Services · US

Funding

A comparison of cognitive and dynamic therapy for MDD in community settingsR01HS018440 · AHRQ · UNIVERSITY OF PENNSYLVANIA · PI GIBBONS, MARY BETH · 2009 to 2013
$2.4M
The mechanisms of cognitive and dynamic therapy in community settings.R01MH092363 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI CRITS-CHRISTOPH, PAUL F · 2011 to 2014
$1.1M
Comparative Effectiveness of Interventions for Depression in the CommunityK02HS022124 · AHRQ · UNIVERSITY OF PENNSYLVANIA · PI GIBBONS, MARY BETH · 2013 to 2017
$775k
AHRQ HHS K02 HS022124AHRQ HHS R01 HS018440NIMH NIH HHS R01 MH092363
6 · The paper itself

Abstract

importanceDynamic psychotherapy (DT) is widely practiced in the community, but few trials have established its effectiveness for specific mental health disorders relative to control conditions or other evidence-based psychotherapies.

objectiveTo determine whether DT is not inferior to cognitive therapy (CT) in the treatment of major depressive disorder (MDD) in a community mental health setting. DESIGN, SETTING, AND

participantsFrom October 28, 2010, to July 2, 2014, outpatients with MDD were randomized to treatment delivered by trained therapists. Twenty therapists employed at a community mental health center in Pennsylvania were trained by experts in CT or DT. A total of 237 adult outpatients with MDD seeking services at this site were randomized to 16 sessions of DT or CT delivered across 5 months. Final assessment was completed on December 9, 2014, and data were analyzed from December 10, 2014, to January 14, 2016.

interventionsShort-term DT or CT. MAIN OUTCOMES AND MEASURES: Expert blind evaluations with the 17-item Hamilton Rating Scale for Depression.

resultsAmong the 237 patients (59 men [24.9%]; 178 women [75.1%]; mean [SD] age, 36.2 [12.1] years) treated by 20 therapists (19 women and 1 man; mean [SD] age, 40.0 [14.6] years), 118 were randomized to DT and 119 to CT. A mean (SD) difference between treatments was found in the change on the Hamilton Rating Scale for Depression of 0.86 (7.73) scale points (95% CI, -0.70 to 2.42; Cohen d, 0.11), indicating that DT was statistically not inferior to CT. A statistically significant main effect was found for time (F1,198 = 75.92; P = .001). No statistically significant differences were found between treatments on patient ratings of treatment credibility. Dynamic psychotherapy and CT were discriminated from each other on competence in supportive techniques (t120 = 2.48; P = .02), competence in expressive techniques (t120 = 4.78; P = .001), adherence to CT techniques (t115 = -7.07; P = .001), and competence in CT (t115 = -7.07; P = .001). CONCLUSIONS AND RELEVANCE: This study suggests that DT is not inferior to CT on change in depression for the treatment of MDD in a community mental health setting. The 95% CI suggests that the effects of DT are equivalent to those of CT.

trial registrationclinicaltrials.gov Identifier: NCT01207271.

Indexed as

Cognitive Behavioral TherapyCommunity Mental Health CentersPsychotherapy, PsychodynamicAdultFemaleHumansMajor Depressive DisorderMaleMiddle AgedPennsylvaniaTreatment Outcome

Identifiers

PMID27487573
PMCPMC5627972
OpenAlexW2505690247

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.