ArticleeLife2016
Spatial tuning and brain state account for dorsal hippocampal CA1 activity in a non-spatial learning task.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Place and behavioral modulation of hippocampal neurons during immobility.Nature communications · 2026Article
- Hippocampal conditioning code dominates and disrupts the place code.bioRxiv : the preprint server for biology · 2026Article
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- Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types.Science (New York, N.Y.) · 2022Article
- The hearing hippocampus.Progress in neurobiology · 2022Review
- Do hippocampal pyramidal cells respond to nonspatial stimuli?Physiological reviews · 2021Review
- Refinement and Reactivation of a Taste-Responsive Hippocampal Network.Current biology : CB · 2020Article
- Differential responsivity of neurons in perirhinal cortex, lateral entorhinal cortex, and dentate gyrus during time-bridging learning.Hippocampus · 2019Article
- Interaction of Taste and Place Coding in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- A method for combining multiple-units readout of optogenetic control with natural stimulation-evoked eyeblink conditioning in freely-moving mice.Scientific reports · 2019Article
- Dynamics of a hippocampal neuronal ensemble encoding trace fear memory revealed by in vivo Ca2+ imaging.PloS one · 2019Article
- Inhibition shapes the organization of hippocampal representations.Hippocampus · 2018Review
- Methods for Assessment of Memory Reactivation.Neural computation · 2018Article
- Deciphering Neural Codes of Memory during Sleep.Trends in neurosciences · 2017Review
- Brain State Dependence of Hippocampal Subthreshold Activity in Awake Mice.Cell reports · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The hippocampus is a brain area crucial for episodic memory in humans. In contrast, studies in rodents have highlighted its role in spatial learning, supported by the discovery of place cells. Efforts to reconcile these views have found neurons in the rodent hippocampus that respond to non-spatial events but have not unequivocally dissociated the spatial and non-spatial influences on these cells. To disentangle these influences, we trained freely moving rats in trace eyeblink conditioning, a hippocampally dependent task in which the animal learns to blink in response to a tone. We show that dorsal CA1 pyramidal neurons are all place cells, and do not respond to the tone when the animal is moving. When the animal is inactive, the apparent tone-evoked responses reflect an arousal-mediated resumption of place-specific firing. These results suggest that one of the main output stages of the hippocampus transmits only spatial information, even in this non-spatial task.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.