ArticleJournal of clinical neurology (Seoul, Korea)2016
Detection of Listeria monocytogenes in CSF from Three Patients with Meningoencephalitis by Next-Generation Sequencing.
Article in Journal of clinical neurology (Seoul, Korea), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early trigeminal nerve involvement in Listeria monocytogenes rhombencephalitis: case series and systematic review.Journal of neurology · 2017Pooled it
- Aggressive brainstem listeria abscess in an immunocompetent individual: A case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- The value of mNGS in the diagnosis of central nervous system infections in immunodeficient hosts with decompensated cirrhosis complicated byFrontiers in medicine · 2026Article
- Metagenomic Sequencing for Diagnosing Listeria-Induced Rhombencephalitis in Patient and Contaminated Cheese Samples: A Case Report.International journal of molecular sciences · 2025Article
- The impact of bronchoalveolar lavage fluid metagenomics next-generation sequencing on the diagnosis and management of patients with suspected pulmonary infection.Frontiers in cellular and infection microbiology · 2025Article
- Exploring the appropriate situation of performing CSF mNGS in patients with proposed intracranial infections.BMC neurology · 2024Article
- Imaging modalities in neurolisteriosis: a literature review.Polish journal of radiology · 2024Review
- Clinical value of metagenomic sequencing in system evaluation of potential donors and donor-derived infection in kidney transplantation.American journal of translational research · 2024Article
- Clinical and Bacterial Characteristics of Bloodstream Infections Caused byThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024Article
- A Repertoire of Clinical Non-Dermatophytes Moulds.Journal of fungi (Basel, Switzerland) · 2023Review
- Application of next-generation metagenomic sequencing in the diagnosis and treatment of acute spinal infections.Heliyon · 2023Article
- A case report of diagnosis and dynamic monitoring ofOpen life sciences · 2023Article
- Metagenomic next-generation sequencing of bronchoalveolar lavage fluid assists in the diagnosis of pathogens associated with lower respiratory tract infections in children.Frontiers in cellular and infection microbiology · 2023Article
- The Clinical Characteristics, Diagnostic Methods, Treatment, and Outcomes ofInfection and drug resistance · 2023Article
- Clinical Characteristics and Treatment ofInfection and drug resistance · 2023Article
- Inconsistency analysis between metagenomic next-generation sequencing results of cerebrospinal fluid and clinical diagnosis with suspected central nervous system infection.BMC infectious diseases · 2022Article
- Brainstem abscesses caused byWorld journal of clinical cases · 2022Article
- The diagnostic value of metagenomic next-generation sequencing for identifyingFrontiers in cellular and infection microbiology · 2022Article
- Listeriosis in a Metropolitan Hospital: Is Targeted Therapy a Risk Factor for Infection?Frontiers in medicine · 2022Article
- Diagnostic Value and Clinical Application of mNGS for Post-Liver Transplantation Infection: A Cross-Sectional Study With Case Reports.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeEncephalitis caused by Listeria monocytogenes (L. monocytogenes) is rare but sometimes fatal. Early diagnosis is difficult using routine cerebrospinal fluid (CSF) tests, while next-generation sequencing (NGS) is increasingly being used for the detection and characterization of pathogens.
methodsThis study set up and applied unbiased NGS to detect L. monocytogenes in CSF collected from three cases of clinically suspected listeria meningoencephalitis.
resultsThree cases of patients with acute/subacute meningoencephalitis are reported. Magnetic resonance imaging and blood cultures led to a suspected diagnosis of L. monocytogenes, while the CSF cultures were negative. Unbiased NGS of CSF identified and sequenced reads corresponding to L. monocytogenes in all three cases.
conclusionsThis is the first report highlighting the feasibility of applying NGS of CSF as a diagnostic method for central nervous system (CNS) L. monocytogenes infection. Routine application of this technology in clinical microbiology will significantly improve diagnostic methods for CNS infectious diseases.
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