Evidence map›Paper›PMID 27486772›Full record

ReviewOncotarget2016

Decellularized scaffolds in regenerative medicine.

Yaling Yu, Ali Alkhawaji, Yuqiang Ding, Jin Mei

Abstract readReview
In one paragraph

Review in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Pericardium decellularization in a one-day, two-step protocol.Molecular and cellular biochemistry · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Applications of synthetic biology in medical and pharmaceutical fields.Signal transduction and targeted therapy · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Towards organoid culture without Matrigel.Communications biology · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaling YuDepartment of Anatomy, Wenzhou Medical University, Wenzhou, China.
Ali AlkhawajiDepartment of Anatomy, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Yuqiang DingInstitute of Neuroscience, Wenzhou Medical University, Wenzhou, China.
Jin MeiDepartment of Anatomy, Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic organ transplantation remains the ultimate solution for end-stage organ failure. Yet, the clinical application is limited by the shortage of donor organs and the need for lifelong immunosuppression, highlighting the importance of developing effective therapeutic strategies. In the field of regenerative medicine, various regenerative technologies have lately been developed using various biomaterials to address these limitations. Decellularized scaffolds, derived mainly from various non-autologous organs, have been proved a regenerative capability in vivo and in vitro and become an emerging treatment approach. However, this regenerative capability varies between scaffolds as a result of the diversity of anatomical structure and cellular composition of organs used for decellularization. Herein, recent advances in scaffolds based on organ regeneration in vivo and in vitro are highlighted along with aspects where further investigations and analyses are needed.

Indexed as

RegenerationAnimalsBiocompatible MaterialsBrainHeartHumansKidneyLiverLungPancreasRegenerative MedicineSkin Physiological PhenomenaSpinal CordTissue EngineeringTissue ScaffoldsBiocompatible Materialsdecellularized scaffoldextracellular matrixin vivo/in vitroorganregeneration

Identifiers

PMID27486772
PMCPMC5295461

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.