ArticleFrontiers in neurology2016
Aging Increases Compensatory Saccade Amplitude in the Video Head Impulse Test.
Article in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
- Normal Gain with Corrective Saccades in the Video Head Impulse Test: Clinical Implications and Diagnostic Considerations.Diagnostics (Basel, Switzerland) · 2026Article
- Eye Drift Signal Analysis Caused by Goggle Slippage in vHIT Measurements: A Signal Processing Perspective.Sensors (Basel, Switzerland) · 2026Article
- Can video head impulse testing aid differential assessment of suspected vestibular migraine attacks?Frontiers in neurology · 2026Review
- The Use of vHIT in the Differential Diagnosis Between Vestibular Migraine and Meniere's Disease: A Systematic Review and Meta-Analysis.Audiology research · 2025Review
- Normal horizontal VOR gain and catch-up saccades: still a diagnostic dilemma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Normal Variations of Video Head Impulse Test in Adult Populations at Peak Head Velocity of Below 150 Degrees/Second.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Do measures of gain asymmetry and catch-up saccades improve video head impulse test agreement with caloric results?Clinical neurophysiology practice · 2024Article
- Vestibulo-Ocular Reflex in the Aging Population.Sisli Etfal Hastanesi tip bulteni · 2024Article
- Molecular and Functional Changes to Postsynaptic Cholinergic Signaling in the Vestibular Sensory Organs of Aging C57BL/6 Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Saccades of video head impulse test in Meniere's disease and Vestibular Migraine: What can we learn from?Journal of otology · 2023Article
- Effects of saccade delay, side of deficit, and training on detection of catch-up saccades during head-impulse test in virtual-reality-enhanced mannequin.Scientific reports · 2023Article
- Presence of corrective saccades in patients with normal vestibulo-ocular reflex gain in video head impulse test.Frontiers in neurology · 2023Article
- The reliability of a subtype-determining questionnaire in efficient benign paroxysmal positional vertigo diagnosis in geriatrics.Frontiers in aging neuroscience · 2023Article
- Test-Retest Reliability, Effects of Age and Comparison of Horizontal 2 Semicircular Canals Gain Values between Head Impulse and Suppression Head Impulse Paradigms.The journal of international advanced otology · 2023Article
- Unique compensatory oculomotor behavior in people living with multiple sclerosis.Journal of the neurological sciences · 2022Article
- Greater Disability Is Associated with Worse Vestibular and Compensatory Oculomotor Functions in People Living with Multiple Sclerosis.Brain sciences · 2022Article
- The Role of Neck Input in Producing Corrective Saccades in the Head Impulse Test.Frontiers in neurology · 2022Article
- Vestibular and balance function in veterans with chronic dizziness associated with mild traumatic brain injury and blast exposure.Frontiers in neurology · 2022Article
- The Relationship Between Rotary Chair and Video Head Impulse Testing in Children and Young Adults With Cochlear Implants.American journal of audiology · 2020Article
- Aging and the Relationship between Balance Performance, Vestibular Function and Somatosensory Thresholds.The journal of international advanced otology · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveRotational vestibular function declines with age resulting in saccades as a compensatory mechanism to improve impaired gaze stability. Small reductions in rotational vestibulo-ocular reflex (VOR) gain that would be considered clinically normal have been associated with compensatory saccades. We evaluated whether compensatory saccade characteristics varied as a function of age, independent of semicircular canal function as quantified by VOR gain.
methodsHorizontal VOR gain was measured in 243 participants age 27-93 from the Baltimore Longitudinal Study of Aging using video head impulse testing. Latency and amplitude of the first saccade (either covert - occurring during head impulse, or overt - occurring following head impulse) were measured for head impulses with compensatory saccades (n = 2230 head impulses). The relationship between age and saccade latency, as well as the relationship between age and saccade amplitude, were evaluated using regression analyses adjusting for VOR gain, gender, and race.
resultsOlder adults (mean age 75.9) made significantly larger compensatory saccades relative to younger adults (mean age 45.0). In analyses adjusted for VOR gain, there was a significant association between age and amplitude of the first compensatory covert saccade (β = 0.015, p = 0.008). In analyses adjusted for VOR gain, there was a significant association between age and amplitude of the first compensatory overt saccade (β = 0.02, p < 0.001). Compensatory saccade latencies did not vary significantly by age.
conclusionWe observed that aging increases the compensatory catch-up saccade amplitude in healthy adults after controlling for VOR gain. Size of compensatory saccades may be useful in addition to VOR gain for characterizing vestibular function in aging adults.
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