ReviewInterdisciplinary toxicology2015
Lead toxicity: a review.
Review in Interdisciplinary toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03495492 (Dermal Chelation Lowers White Blood Cell Count in Chronic Lymphocytic Leukemia), which is not on this map. Cited by 461 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dermal Chelation Lowers White Blood Cell Count in Chronic Lymphocytic Leukemia
Who cites it
461 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic Review of Metallic, Industrial, and Pharmaceutical Emerging Contaminants in Snow and Ice: A Global Perspective from Polar and High-Mountain Regions.Molecules (Basel, Switzerland) · 2026Pooled it
- Exploring the link between toxic metal exposure and ADHD: a systematic review of pb and hg.Journal of neurodevelopmental disorders · 2024Pooled it
- Elevated Blood Lead Levels Among Refugee Children in Urban Primary Care: A Retrospective Analysis Following Revised CDC Guidelines.Journal of immigrant and minority health · 2026Article
- Embryonic lead (Pb) contact impairs lipid, oxidative, and behavioral markers in zebrafish across multiple generations.Environmental research · 2026Article
- Comparative Efficacy of Coriander Seed Extract-Loaded Selenium Nanoparticles and DMSA in Restoring Antioxidant/Apoptotic Balance of Lead-Induced Hepatotoxicity.Cell biochemistry and biophysics · 2026Article
- Lead Management in Perovskite Photovoltaics: Status and Perspectives.ChemSusChem · 2026Review
- Lead Is Toxic to Neuronal Cells by Inducing Oxidative Stress and Activating Neuroinflammatory Pathways.Brain sciences · 2026Article
- Article
- Sex Differences in Oxidative Stress and Depression-Like Behavior Following Chronic Lead Exposure from Pregnancy to Adulthood.Biological trace element research · 2026Article
- Article
- Changes in the chick liver structure and blood plasma biochemical properties following in ovo administration of acrylamide.Poultry science · 2026Article
- Synthesis of BaZrSACS omega · 2026Article
- Incidental Changes in Urinary Lead Excretion Following Intra-Venous Ca-DTPA Administration in Patients Treated Primarily for Gadolinium Exposure.Journal of xenobiotics · 2026Article
- Waste-to-Resource: Heavy Metal Ions Adsorption from Aqueous Solutions Using Coal Fly Ash and Bone Charcoal.Molecules (Basel, Switzerland) · 2026Article
- Toxic Trace Element Levels in Maternal and Cord Blood Worldwide and Their Impact on Pregnancy: A Narrative Review.Journal of xenobiotics · 2026Review
- Estimated Dietary Lead Exposure Through Aquatic Animal Consumption and Health Symptoms in a Lake-Dependent Community: Evidence from Nong Han Lake, Northeast Thailand.International journal of environmental research and public health · 2026Article
- Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- The effects of nanoplastics on toxicity of metals and metal nanoparticles: molecular mechanisms and health effects.Archives of toxicology · 2026Review
- Heavy Metal Air Pollution: Human Health Effects and Nanomaterial Strategies for Monitoring and Remediation.Biological trace element research · 2026Review
- Lead and cancer: a narrative review and risk of bias assessment (2003-2020).Reviews on environmental health · 2026Review
401 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lead toxicity is an important environmental disease and its effects on the human body are devastating. There is almost no function in the human body which is not affected by lead toxicity. Though in countries like US and Canada the use of lead has been controlled up to a certain extent, it is still used vehemently in the developing countries. This is primarily because lead bears unique physical and chemical properties that make it suitable for a large number of applications for which humans have exploited its benefits from historical times and thus it has become a common environmental pollutant. Lead is highly persistent in the environment and because of its continuous use its levels rise in almost every country, posing serious threats. This article reviews the works listed in the literature with recent updates regarding the toxicity of lead. Focus is also on toxic effects of lead on the renal, reproductive and nervous system. Finally the techniques available for treating lead toxicity are presented with some recent updates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.