Evidence map›Paper›PMID 27486237›Full record

ReviewDiabetes care2016

Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities.

Kristen J Nadeau, Barbara J Anderson, Erika G Berg, Jane L Chiang, Hubert Chou, Kenneth C Copeland, Tamara S Hannon, Terry T-K Huang, Jane L Lynch, Jeff Powell and 3 more

Registry-linked trialAbstract readReviewConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetes care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06117631 (First Thousand Days), which is not on this map. Cited by 203 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06117631 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

First Thousand Days: Prevention of Early Life Obesity in Latino Infants and Toddlers

TypeinterventionalSponsorUniversity of Texas at AustinRan2023 to 2027Enrolled256ConditionsInfant Overweight, Infant Obesity, Infant Overnutrition, Infant DevelopmentArmsCentering Parenting, Bright by Text
3 · Its place in the literature

Who cites it

203 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  11. Once-Weekly Exenatide in Youth With Type 2 Diabetes.Diabetes care · 2022 · on this map
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143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kristen J NadeauDepartment of Pediatrics, University of Colorado School of Medicine, and Department of Endocrinology, Children's Hospital Colorado, Aurora, CO.
Barbara J AndersonSection of Psychology, Department of Pediatrics, Baylor College of Medicine Education at Texas Children's Hospital, Houston, TX.
Erika G BergAmerican Diabetes Association, Alexandria, VA.
Jane L ChiangAmerican Diabetes Association, Alexandria, VA.
Hubert ChouClinical Development, Daiichi Sankyo, New York, NY.
Kenneth C CopelandDepartment of Pediatrics and Harold Hamm Diabetes Center-Children's, The University of Oklahoma College of Medicine, Oklahoma City, OK.
Tamara S HannonIndiana University School of Medicine, Indianapolis, IN.
Terry T-K HuangSchool of Public Health, The City University of New York, New York, NY.
Jane L LynchThe University of Texas Health Science Center at San Antonio, San Antonio, TX.
Jeff PowellPediatrics and Community Health, Northern Navajo Medical Center, Navajo Area Indian Health Service, Shiprock, NM.
Elizabeth SellersDepartment of Pediatrics, Health Sciences Centre Winnipeg, Winnipeg, Canada.
William V TamborlaneDepartment of Pediatric Endocrinology and Yale Center for Clinical Investigation, Yale School of Medicine, New Haven, CT.
Philip ZeitlerDepartment of Pediatrics, University of Colorado School of Medicine, and Department of Endocrinology, Children's Hospital Colorado, Aurora, CO philip.zeitler@childrenscolorado.org.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Functional aspects of SREBP1c in intact skeletal muscleK01DK067403 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI MACLEAN, PAUL S · 2005 to 2007
$397k
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS P30 DK045735
6 · The paper itself

Abstract

Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes in children is different not only from type 1 but also from type 2 diabetes in adults. Understanding the unique pathophysiology of type 2 diabetes in youth, as well as the risk of complications and the psychosocial impact, will enable industry, academia, funding agencies, advocacy groups, and regulators to collectively evaluate both current and future research, treatment, and prevention approaches. This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.

Indexed as

Delivery of Health CareAdolescentAge of OnsetAllostasisChildDiabetes ComplicationsDiabetes Mellitus, Type 2Diet TherapyDisease ManagementEthnicityExercise TherapyHumansHypoglycemic AgentsMinority GroupsRiskRisk Reduction BehaviorHypoglycemic Agents

Identifiers

PMID27486237
PMCPMC5314694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.