Evidence map›Paper›PMID 27486149›Full record

SynthesisCanadian journal of psychiatry. Revue canadienne de psychiatrie2016

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 6. Special Populations: Youth, Women, and the Elderly.

Glenda M MacQueen, Benicio N Frey, Zahinoor Ismail, Natalia Jaworska, Meir Steiner, Ryan J Van Lieshout, Sidney H Kennedy, Raymond W Lam, Roumen V Milev, Sagar V Parikh and 2 more

Erratum issued 3 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 95 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 12 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04714164 naterminatednot on this mapstarted 2021, after this paper: background citation

Feasibility of Delivering Group Cognitive Behavioral Therapy for Older Adults With Depression and Anxiety by Telehealth

TypeinterventionalSponsorNova Scotia Health AuthorityRan2021 to 2023Enrolled5ConditionsMajor Depressive Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic DisorderArmsGroup Cognitive Behavioral Therapy
NCT05814640 phase1 / phase2recruitingnot on this mapstarted 2023, after this paper: background citation

Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD): a Pragmatic Clinical Trial

TypeinterventionalSponsorFirst Affiliated Hospital of Chongqing Medical UniversityRan2023 to 2027Enrolled520ConditionsDepression, SequestraArmsFluoxetine, Sertraline, Vortioxetine, Duloxetine, Aripiprazole
NCT06597448 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Public Health Nurse-Peer Co-Delivered Group Cognitive Behavioral Therapy for Postpartum Depression: A Randomized Controlled Trial

TypeinterventionalSponsorMcMaster UniversityRan2024 to 2028Enrolled170ConditionsPostpartum DepressionArmsCognitive Behavioral Therapy for Postpartum Depression (PPD)
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 12 syntheses or guidelines pooled it, 246 citations in OpenAlex.

  1. FIGO best practice recommendations for the mental health of women at menopausal age.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Guideline
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Trial
  14. Trial
  15. Trial
  16. Comparative Efficacy of Interventions for the Prevention and Treatment of Postpartum Depression: A Bayesian Network Meta-analysis.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Article

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Glenda M MacQueenDepartment of Psychiatry, University of Calgary, Calgary, Alberta gmmacque@ucalgary.ca.
Benicio N FreyDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario.
Zahinoor IsmailDepartment of Psychiatry, University of Calgary, Calgary, Alberta.
Natalia JaworskaDepartment of Psychiatry, McGill University, Montréal, Quebec.
Meir SteinerDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario.
Ryan J Van LieshoutDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario.
Sidney H KennedyDepartment of Psychiatry, University of Toronto, Toronto, Ontario.
Raymond W LamDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia.
Roumen V MilevDepartment of Psychiatry, Queen's University, Kingston, Ontario.
Sagar V ParikhDepartment of Psychiatry, University of Toronto, Toronto, Ontario Department of Psychiatry, University of Michigan, Ann Arbor, Michigan.
Arun V RavindranDepartment of Psychiatry, University of Toronto, Toronto, Ontario.
CANMAT Depression Work Group
McMaster University · CAUniversity of Toronto · CAUniversity of Calgary · CAMcGill University · CAQueen's University · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Canadian Network for Mood and Anxiety Treatments (CANMAT) conducted a revision of the 2009 guidelines by updating the evidence and recommendations. The scope of the 2016 guidelines remains the management of major depressive disorder (MDD) in adults, with a target audience of psychiatrists and other mental health professionals.

methodsUsing the question-answer format, we conducted a systematic literature search focusing on systematic reviews and meta-analyses. Evidence was graded using CANMAT-defined criteria for level of evidence. Recommendations for lines of treatment were based on the quality of evidence and clinical expert consensus. This section on "Special Populations" is the sixth of six guidelines articles.

resultsRecent studies inform the treatment of MDD in children and adolescents, pregnant and breastfeeding women, women in perimenopause or menopause, and the elderly. Evidence for efficacy of treatments in these populations is more limited than for the general adult population, however, and risks of treatment in these groups are often poorly studied and reported.

conclusionsDespite the limited evidence base, extant data and clinical experience suggest that each of these special populations can benefit from the systematic application of treatment guidelines for treatment of MDD.

Indexed as

PerimenopauseAdolescent PsychiatryAdultAgedCanadaChildChild PsychiatryEvidence-Based MedicineFemaleGeriatric PsychiatryHumansMajor Depressive DisorderPractice Guidelines as TopicPregnancyPregnancy Complicationschild and adolescent psychiatryclinical practice guidelinesevidence-based medicinegeriatric psychiatrymajor depressive disordermaternal healthmeta-analysisperinatalpostpartumsystematic reviews

Identifiers

PMID27486149
PMCPMC4994788
OpenAlexW2489205254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.