ReviewCurrent neurology and neuroscience reports2016
Impact of Infection on Stroke Morbidity and Outcomes.
Review in Current neurology and neuroscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Immunomodulation for stroke-associated pneumonia: a systematic review of mechanistic insight and emerging therapeutic strategies in animal models.Frontiers in immunology · 2026Pooled it
- Impact of mobile health and telehealth technology on medication adherence of stroke patients: a systematic review and meta-analysis of randomized controlled trials.International journal of clinical pharmacy · 2022Pooled it
- The Mediating Role of Hypoalbuminemia in the Association Between Frailty and Poor Outcomes in Stroke Patients.Nursing open · 2026Article
- Infection as a Key Determinant of Readmission in Stroke Patients: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2025Review
- Exploring the stroke burden linked to Kidney dysfunction: trends, predictive insights, and health inequalities.Frontiers in neurology · 2025Article
- A novel prediction method for intracerebral hemorrhage-associated pneumonia: A single center analysis.PloS one · 2025Article
- Systemic inflammatory response index as a predictor of stroke-associated pneumonia in patients with acute ischemic stroke treated by thrombectomy: a retrospective study.BMC neurology · 2024Article
- Outcomes and risk factors for infection after endovascular treatment in patients with acute ischemic stroke.CNS neuroscience & therapeutics · 2024Article
- A Role for Systemic Inflammation in Stroke-Associated Infection and the Long-Term Prognosis of Acute Ischemic Stroke: A Mediation Analysis.Journal of inflammation research · 2024Article
- Thrombo-inflammatory prognostic score can predict the outcome of stroke: a retrospective cohort study.Frontiers in aging neuroscience · 2024Article
- Stroke rehabilitation: from diagnosis to therapy.Frontiers in neurology · 2024Review
- Long-term functional outcome and quality of life 2.5 years after thrombolysis in acute ischemic stroke.Neurological research and practice · 2023Article
- The gastrointestinal-brain-microbiota axis: a promising therapeutic target for ischemic stroke.Frontiers in immunology · 2023Review
- Nrf2 Regulates Oxidative Stress and Its Role in Cerebral Ischemic Stroke.Antioxidants (Basel, Switzerland) · 2022Review
- Blood pressure variability related to early outcome of acute ischemia stroke in a prospective observational study.Medicine · 2022Observational
- The Role of Concomitant Nrf2 Targeting and Stem Cell Therapy in Cerebrovascular Disease.Antioxidants (Basel, Switzerland) · 2022Review
- New Insights into Stroke Prevention and Treatment: Gut Microbiome.Cellular and molecular neurobiology · 2022Review
- Novel Predictors of Stroke-Associated Pneumonia: A Single Center Analysis.Frontiers in neurology · 2022Article
- Monocyte-to-lymphocyte ratio as a predictor of stroke-associated pneumonia: A retrospective study-based investigation.Brain and behavior · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Each year, millions of persons worldwide are disabled by stroke. The burden of stroke is expected to increase as a consequence of growth in our elderly population. Outcome is dependent upon limitation of secondary medical processes in the acute setting that lead to deterioration and increased long-term disability. The prevalence of infection after stroke is greater that seen in other medical conditions with similar acuity and its impact upon morbidity and mortality is substantial. Physical impairment and immune modulation are chief determinants in rate of infection after stroke. Each of these factors has been a target for therapeutic intervention. Current best practices for acute stroke management implement strategies for prevention, prompt identification, and treatment of infection. Novel therapies are currently being explored which have the opportunity to greatly minimize infectious complications following stroke. Fever commonly accompanies infection and independently influences stroke outcome. Targeted temperature management provides an additional chance to improve stroke recovery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.