ArticleScientific reports2016
Label-free optical quantification of structural alterations in Alzheimer's disease.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging.Biophysics reports · 2026Article
- Polarimetric analysis of the Alzheimer's pathology in excised mouse brain tissue.Journal of biomedical optics · 2026Article
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- Scattering polarimetry enables correlative nerve fiber imaging and multimodal analysis.Scientific reports · 2025Article
- Revealing 3D microanatomical structures of unlabeled thick cancer tissues using holotomography and virtual H&E staining.Nature communications · 2025Article
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- Permittivity tensor imaging: modular label-free imaging of 3D dry mass and 3D orientation at high resolution.Nature methods · 2024Article
- Multi-contrast digital histopathology of mouse organs using quantitative phase imaging and virtual staining.Biomedical optics express · 2023Article
- Quantification of structural heterogeneity in H&E stained clear cell renal cell carcinoma using refractive index tomography.Biomedical optics express · 2023Article
- Decoherence of photon entanglement by transmission through brain tissue with Alzheimer's disease.Biomedical optics express · 2022Article
- Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy.Biomedical optics express · 2022Article
- Preprocessing methods for quantitative phase image stitching.Biomedical optics express · 2022Article
- Synthetic aperture interference light (SAIL) microscopy for high-throughput label-free imaging.Applied physics letters · 2021Article
- The effect of pupil transmittance on axial resolution of reflection phase microscopy.Scientific reports · 2021Article
- Article
- Influence of the anatomical features of different brain regions on the spatial localization of fiber photometry signals.Biomedical optics express · 2021Article
- Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity.Light, science & applications · 2021Article
- High-resolution impedance mapping using electrically activated quantitative phase imaging.Light, science & applications · 2021Article
- The Progress of Label-Free Optical Imaging in Alzheimer's Disease Screening and Diagnosis.Frontiers in aging neuroscience · 2021Review
- High spatially sensitive quantitative phase imaging assisted with deep neural network for classification of human spermatozoa under stressed condition.Scientific reports · 2020Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a wide-field quantitative label-free imaging of mouse brain tissue slices with sub-micrometre resolution, employing holographic microscopy and an automated scanning platform. From the measured light field images, scattering coefficients and anisotropies are quantitatively retrieved by using the modified the scattering-phase theorem, which enables access to structural information about brain tissues. As a proof of principle, we demonstrate that these scattering parameters enable us to quantitatively address structural alteration in the brain tissues of mice with Alzheimer's disease.
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