Evidence map›Paper›PMID 27485253›Full record

ArticleLasers in medical science2016

Evaluation of synergistic effects of sulforaphene with photodynamic therapy in human cervical cancer cell line.

R Biswas, A Mondal, S Chatterjee, J C Ahn

Abstract read
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Article in Lasers in medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

R BiswasBeckman Laser Institute Korea, Dankook University, Cheonan, Republic of Korea.
A MondalDepartment of Pre-medical Science, Dankook University, Cheonan, 330-714, Republic of Korea.
S ChatterjeeBiomedical Translational Research Institute, Dankook University, Cheonan, Republic of Korea.
J C AhnBeckman Laser Institute Korea, Dankook University, Cheonan, Republic of Korea. jcahn@dankook.ac.kr.
Dankook University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulforaphene from cruciferous vegetable has shown to modulate various signaling pathways of apoptosis. But it has not yet been studied extensively for the cervical cancer treatment. Previous studies show the promising role of photodynamic therapy for cervical cancer. Here, we confirm that sulforaphene can synergistically enhance the efficacy of photodynamic therapy. Human cervical cancer cells HeLa were treated with a very low dose of sulforaphene (2.0 μg/ml) and photodynamic therapy with radachlorin (0.5 μg/ml) at a fluence of 27 J/cm

Indexed as

PhotochemotherapyApoptosisBlotting, WesternCell SurvivalFemaleFlow CytometryG1 PhaseHeLa CellsHumansIsothiocyanatesMembrane Potential, MitochondrialSignal TransductionUterine Cervical NeoplasmsIsothiocyanatessulphorapheneApoptosisPDTSulforapheneSynergy

Identifiers

PMID27485253
OpenAlexW2493101166

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.