Evidence map›Paper›PMID 27485152›Full record

ArticleClinical rheumatology2016

Prevalence of cardiovascular-related comorbidity in ankylosing spondylitis, psoriatic arthritis and psoriasis in primary care: a matched retrospective cohort study.

Nadeem Ahmed, James A Prior, Ying Chen, Richard Hayward, Christian D Mallen, Samantha L Hider

Abstract read
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In one paragraph

Article in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Brazilian Society of Rheumatology 2020 guidelines for psoriatic arthritis.Advances in rheumatology (London, England) · 2021
    Pooled it
  3. Pooled it
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  15. Observational
  16. Article
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  18. Comorbidities in Spondyloarthritis.Frontiers in medicine · 2018
    Review
  19. Measurement properties of the EQ-5D-5L compared to the EQ-5D-3L in psoriasis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017
    Article
  20. Role of Inflammatory Diseases in Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadeem AhmedResearch Institute for Primary Care and Health Sciences, Keele University, Keele, ST5 5BG, UK.
James A PriorResearch Institute for Primary Care and Health Sciences, Keele University, Keele, ST5 5BG, UK. j.a.prior@keele.ac.uk.
Ying ChenResearch Institute for Primary Care and Health Sciences, Keele University, Keele, ST5 5BG, UK.
Richard HaywardResearch Institute for Primary Care and Health Sciences, Keele University, Keele, ST5 5BG, UK.
Christian D MallenResearch Institute for Primary Care and Health Sciences, Keele University, Keele, ST5 5BG, UK.
Samantha L HiderResearch Institute for Primary Care and Health Sciences, Keele University, Keele, ST5 5BG, UK.

Funding

Department of Health WMCLAHRC-2014-1
6 · The paper itself

Abstract

The aim of this study is to compare the prevalence of cardiovascular (CVD)-related comorbidities in patients with ankylosing spondylitis (AS), psoriatic arthritis (PsA) or psoriasis (Ps) in UK primary care against matched cohorts. Matched retrospective cohort study used a primary care consultation database. Three cohorts were constructed using all patients with a Read code diagnosis of AS, PsA or Ps between 1999 and 2009; each cohort was then compared in a 1:4 ratio to a matched cohort. The prevalence of CVD-related comorbidities (hypertension, ischaemic heart disease, hyperlipidaemia and diabetes mellitus) were identified by the first consultation of a comorbid Read code, in those with an inflammatory condition of interest. The prevalence of CVD-related comorbidities was compared between each inflammatory cohort and their matched cohort using Fisher's exact test. Ninety-four AS, 106 PsA and 290 Ps patients were identified. Compared with matched cohorts, the most prevalent CVD-related comorbidity in patients with AS was hypertension (35 (37.2 %) vs. 96 matched (25.5 %), p = 0.03); this was also the case for PsA (41 (38.7 %) vs. 114 matched (26.9 %), p = 0.02). No differences were seen in the prevalence of other CVD-related comorbidities in those with AS, PsA or Ps compared to their matched cohorts. Our findings provide UK comparisons of CVD-related comorbidities in patients with AS, PsA and Ps alone; specifically, demonstrating increased prevalence of hypertension in AS and PsA cohorts compared to their matched cohorts. This further supports the argument for more evidence in the need for screening and intervention around CVD comorbidities in inflammatory conditions.

Indexed as

AdultAgedArthritis, PsoriaticCardiovascular DiseasesComorbidityDiabetes ComplicationsFemaleHumansHypertensionInflammationMaleMiddle AgedPrevalencePrimary Health CarePsoriasisRetrospective StudiesAnkylosing spondylitisCardiovascular diseasePrimary carePsoriasisPsoriatic arthritis

Identifiers

PMID27485152

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.