Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017
MRI-based ACL graft maturity does not predict clinical and functional outcomes during the first year after ACL reconstruction.
Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative assessment of graft maturity after anterior cruciate ligament reconstruction using different graft types: a systematic review.Journal of orthopaedic surgery and research · 2026Pooled it
- Can MRI predict return to sport after anterior cruciate ligament reconstruction? A systematic review of the literature.La Radiologia medica · 2025Pooled it
- Anterior cruciate ligament grafts display differential maturation patterns on magnetic resonance imaging following reconstruction: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Pooled it
- Prospective MRI-Based Comparison of Graft Maturation After ACL Reconstruction Using Quadriceps Versus Hamstring Tendon Autograft.Orthopaedic journal of sports medicine · 2026Article
- MRI Evaluation of Graft Remodeling After Transphyseal Anterior Cruciate Ligament Reconstruction in Pediatric Patients: A 5-Year Follow-up.Orthopaedic journal of sports medicine · 2026Article
- Longitudinal Multiparametric Quantitative MRI Evaluation of Graft Maturity Following Anterior Cruciate Ligament Reconstruction: A One-Year Prospective Observational Study.Diagnostics (Basel, Switzerland) · 2026Article
- Effect of Hyperbaric Oxygen Therapy on Early MRI-Based Graft Healing Following ACL Reconstruction With Hamstring Autografts.Orthopaedic journal of sports medicine · 2026Article
- Autograft maturation assessed by sequential quantitative MR T2 mapping and its correlation with patient-reported outcomes and return to sports during the first year after anterior cruciate ligament reconstruction.Journal of orthopaedic surgery and research · 2026Article
- Reliability of anterior cruciate ligament (ACL) graft signal intensity measurement on MRI: a novel method with intra- and interrater analysis over a 1-week interval.Polish journal of radiology · 2026Article
- Magnetic resonance imaging follow-up after anterior cruciate ligament reconstruction.BMC medical imaging · 2025Article
- Why Should Return to Sport Be Delayed by up to Two Years After ACL Reconstruction? A Narrative Review of the Biological, Surgical and Rehabilitation Evidence.Journal of clinical medicine · 2025Review
- Prospective Magnetic Resonance Imaging Assessment of Capsulolabral Repair in Athletes With Anterior Glenohumeral Instability: Does Cicatrization Exist?Orthopaedic journal of sports medicine · 2025Article
- Anterior Cruciate Ligament Return to Play: "A Framework for Decision Making".Journal of clinical medicine · 2025Article
- [A study of early graft healing after anterior cruciate ligament reconstruction in over-the-top position].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Feasibility of a UTE Stack-of-Spirals Sequence for Biexponential TNMR in biomedicine · 2025Article
- SHORT-TERM MRI EVALUATION OF CAPSULOLABRAL REPAIR IN ATHLETES WITH ANTERIOR GLENOHUMERAL INSTABILITY: CORRELATION WITH CLINICAL OUTCOMES.Acta ortopedica brasileira · 2025Article
- Comprehensive evaluation of magnetic resonance imaging sequences for signal intensity based assessment of anterior cruciate ligament healing following surgical treatment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Periosteal wrapping of the hamstring tendon autograft improves graft healing and prevents tunnel widening after anterior cruciate ligament anatomic reconstruction.Archives of orthopaedic and trauma surgery · 2024Article
- Association of Graft Maturity on MRI With Return to Sports at 9 Months After Primary Single-Bundle ACL Reconstruction With Autologous Hamstring Graft.Orthopaedic journal of sports medicine · 2024Article
- Comment on: "Return to Sports: A Risky Business? A Systematic Review with Meta-analysis of Risk Factors for Graft Rupture Following ACL Reconstruction".Sports medicine (Auckland, N.Z.) · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine whether magnetic resonance image (MRI)-based graft maturity predicts clinical and functional scores during the first year after ACL reconstruction.
methodsPatients with unilateral ACL reconstruction were prospectively invited to participate in this study, and they were examined using a 3.0-T MRI scan at 3, 6, and 12 months after the operation. Clinical examinations were performed on the same day, including subjective functional examinations, physical examinations and the KT-1000 test. MRI measurements were focused on the graft signal intensity of the ACL graft using the signal/noise quotient value from a region of interest analysis.
resultsFinally, a total of 38 participants with ACL reconstruction were recruited for this study, including 21 with autograft tendons and 17 with allograft tendons. Generally, the signal/noise quotient values of the ACL grafts increased from 3 to 6 months and then decreased from 6 to 12 months. There was no significant association between graft signal/noise quotient value and IKDC, Lysholm, or Tegner scores at each time point. Graft signal/noise quotient value had a significant positive association with ATTD for the cohort (p = 0.002) and for the autograft group (p = 0.004) at 3 months. However, there was no significant association between graft signal/noise quotient value and ATTD at 6 or 12 months, respectively.
conclusionThe MRI-based graft maturity does not have the ability to predict clinical and functional outcomes in patients at the first-year follow-up. Graft maturity should not be used as an objective test to determine the appropriate time to return to sports during the first year after ACL reconstruction. The results from this study will allow clinicians to determine graft-specific health to determine whether the graft is healed enough to return to sports during the first postoperative year. LEVEL OF EVIDENCE: III.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.