SynthesisCancer medicine2016
Clinicopathological feature and prognosis of primary hepatic gastrointestinal stromal tumor.
Synthesis in Cancer medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Primary hepatic gastrointestinal stromal tumor with right adrenal gland invasion: A case report and systematic literature review.Medicine · 2019Pooled it
- Clinicopathological feature and prognosis of primary hepatic gastrointestinal stromal tumor.Cancer medicine · 2016Pooled it
- Trial
- Atypical Cystic Primary Hepatic GIST: A Case Report of Rare Presentation and Long-Term Survival.Current oncology (Toronto, Ont.) · 2025Article
- A case of primary gastrointestinal stromal tumor of the liver.Radiology case reports · 2023Article
- Primary Hepatic Extra-gastrointestinal Stromal Tumors: Molecular Pathogenesis, Immunohistopathology, and Treatment.Journal of clinical and translational hepatology · 2023Review
- Article
- A case of primary hepatic stromal tumour misdiagnosed as a liver cyst.The Journal of international medical research · 2022Article
- Case report: 10-year survival of a patient with a primary hepatic gastrointestinal stromal tumor.Frontiers in oncology · 2022Article
- A novel nomogram for predicting liver metastasis in patients with gastrointestinal stromal tumor: a SEER-based study.BMC surgery · 2020Article
- Influence of hepatic neoplasia on life expectancy in dogs.Veterinary world · 2020Article
- Tumor volume increases the predictive accuracy of prognosis for gastric cancer: A retrospective cohort study of 3409 patients.Oncotarget · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compared to gastric gastrointestinal stromal tumor (GIST), hepatic GIST is very rare in clinic. Reports on clinicopathological feature and prognosis of this rare disease are limited in literature. The purpose of this study was, therefore, to summarize clinical and pathological features as well as prognosis of the primary hepatic GIST. One case of primary hepatic GIST from our center and 22 cases reported in MEDLINE or China National Knowledge Infrastructure (CNKI) were enrolled into this study. Clinicopathological features as well as survival data of hepatic GIST were analyzed and compared with 297 gastric GISTs and 59 small intestinal GISTs from our center. Majority of the 22 cases (95.7%) of hepatic GIST was larger than 5 cm in size, and 75.0% of the tumors were over 5/50 HPF in mitotic index. Most of the hepatic GISTs (85.7%) displayed spindle cell shape in morphology. All of the hepatic GIST (100%) enrolled in this study were classified as high-risk category by the National Institute of Health (NIH) risk classification. The 5-year median disease-free survival (DFS) time was 24.0 months and 5-year disease-specific survival (DSS) rate was 33.3%, respectively. Distribution of clinicopathological features was significantly different among hepatic, gastric, and small intestinal GIST. The DFS and DSS of hepatic GIST were significantly lower than those of the other two groups. Majority of the hepatic GIST is large in size and highly malignant. Prognosis of the primary hepatic GIST is worse than that of gastric GIST and small intestinal GIST.
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