ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2016
[Treatment of periprosthetic infections].
Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Trial
- PMMA Bone Cement: Antibiotic Elution and Mechanical Properties in the Context of Clinical Use.Biomedicines · 2022Review
- Gelatin Nanoparticles for Targeted Dual Drug Release out of Alginate-di-Aldehyde-Gelatin Gels.Gels (Basel, Switzerland) · 2022Article
- [Salvage procedure for chronic periprosthetic infection : Use of a rifampicin-loaded polymethyl methacrylate spacer].Unfallchirurgie (Heidelberg, Germany) · 2022Article
- Periprosthetic infections: How do we diagnose and treat? Results of an online survey and comparison with international recommendations.Orthopaedic surgery · 2021Article
- [Implant-associated joint infections].Der Orthopade · 2020Article
- Twenty common errors in the diagnosis and treatment of periprosthetic joint infection.International orthopaedics · 2020Review
- Multiplex PCR Unyvero i60 ITI application improves detection of low-virulent microorganisms in periprosthetic joint infections.International orthopaedics · 2019Article
- [Temporary arthrodesis of the knee in two-stage septic prosthesis exchange : In vitro analysis of adhesion of Staphylococcus aureus on steel and carbon fiber rods].Der Orthopade · 2019Article
- Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers.Journal of orthopaedic surgery and research · 2018Article
- Synovial Fluid Aspiration Should Not Be Routinely Performed during the Two-Stage Exchange of the Knee.BioMed research international · 2018Article
- Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction.Journal of visualized experiments : JoVE · 2017Article
- [Osteosynthesis-associated infections : Epidemiology, definition and diagnosis].Der Unfallchirurg · 2017Review
- [Antibiotic strategies in trauma surgery : Treatment of implant-associated infections].Der Unfallchirurg · 2017Review
- [The significance of biofilm for the treatment of infections in orthopedic surgery : 2017 Update].Der Unfallchirurg · 2017Review
- Low Diagnostic Value of Synovial Aspiration Culture Prior to Reimplantation in Periprosthetic Joint Infection.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing number of prosthesis implantations and higher life expectancy lead to a growing number of periprosthetic infections (PPI). Optimal therapy necessitates interdisciplinary coordination of surgical and antimicrobial treatment. Challenges in the treatment are the increased occurrence of resistant pathogens, selection of adequate antimicrobial and surgical treatment strategies, inappropriate pretreatment and comorbidities of patients. Current treatment concepts lead to a high success rate in terms of infection eradication, when correctly applied. The individual expectations and underlying conditions of each patient must be considered when determining the therapy concept. The first step is to distinguish between acute and chronic infections. In acute infections the prosthesis can be retained but chronic infections necessitate a complete exchange of the prosthesis. Complicating factors, such as compromising soft tissue and bone conditions, osteomyelitis and infections caused by difficult-to-treat bacteria should, however, always be treated by a complete exchange of the prosthesis, even for acute infections. The antimicrobial treatment must be tailored to the causative agent, the surgical strategy as well as comorbidities and drug intolerances of the patient. It is important to distinguish between biofilm-active eradication therapy with rifampicin for gram-positive pathogens and quinolones for gram-negative organisms and suppression therapy. This article gives a structured presentation of the therapy algorithm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.