ArticleScientific reports2016
Fimbriatols A-J, Highly Oxidized ent-Kaurane Diterpenoids from Traditional Chinese Plant Flickingeria fimbriata (B1.) Hawkes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 12 citations in OpenAlex.
- New Derivatives of Caracasine Acid with Anti-Leukemic Activity and Limited Effectiveness in Spheroid Cultures.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Highly Oxygenated Triterpenoids and Diterpenoids from Fructus Rubi (Molecules (Basel, Switzerland) · 2021Article
- Identification ofBMC chemistry · 2019Article
- Symmetry and magnetism allied.Nature materials · 2018Article
- Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots.Molecules (Basel, Switzerland) · 2016Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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Abstract
Fimbriatols A-J (1-10), ten new ent-kaurane diterpenoids possessing differently highly oxidized sites, were isolated from Flickingeria fimbriata (B1.) Hawkes. The structures of these new compounds were determined by HRESI-MS, NMR, CD spectra and X-ray diffraction analysis. Compound 1 displayed moderately inhibitory ratio (48.5%) compared with the positive compound NSC-87877 (81.6%) at the concentration of 0.022 μg/mL. Compounds 7-10 possess 3, 4-seco-ent-kaurane skeleton containing a disaccharide moiety with an unusual linkage at C-2' to C-1'' instead of the common linkage at C-6' to C-1'', and this is the first report in 600 more ent-kauranes found in nature, which might be originated from ent-kaurane diterpenoids through post-modified reactions of Baeyer-Villiger oxygenation and glycosylation.
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