Evidence map›Paper›PMID 27484702›Full record

ArticleSubstance use & misuse2016

Chronic Smoking, Trait Anxiety, and the Physiological Response to Stress.

Nicole Wiggert, Frank H Wilhelm, Motohiro Nakajima, Mustafa al'Absi

Abstract read
In one paragraph

Article in Substance use & misuse, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  8. Review
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  12. Using novel mobile sensors to assess stress and smoking lapse.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020
    Article
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicole Wiggerta Department of Psychology , University of Salzburg , Salzburg , Austria.
Frank H Wilhelma Department of Psychology , University of Salzburg , Salzburg , Austria.
Motohiro Nakajimab Department of Biobehavioral Health and Population Sciences , University of Minnesota Medical School , Duluth , Minnesota , USA.
Mustafa al'Absib Department of Biobehavioral Health and Population Sciences , University of Minnesota Medical School , Duluth , Minnesota , USA.

Funding

Stress, Appetite, and Smoking RelapseR01DA027232 · NIDA · UNIVERSITY OF MINNESOTA · PI AL'ABSI, MUSTAFA, LEE, DUSTIN CLARK · 2010 to 2025
$4.6M
Stress Response and Opioid Dysfunction in Nicotine DependenceR01DA016351 · NIDA · UNIVERSITY OF MINNESOTA DULUTH · PI AL'ABSI, MUSTAFA · 2003 to 2023
$4.5M
Austrian Science Fund FWF W 1233NIDA NIH HHS R01 DA016351NIDA NIH HHS R01 DA027232
6 · The paper itself

Abstract

BACKGROUND AND

objectivesBoth chronic smoking and trait anxiety have been associated with dysregulations in psychobiological stress response systems. However, these factors have not been studied in conjunction. We expected trait anxiety and smoking status to attenuate stress reactivity. Furthermore, we expected an allostatic load effect resulting in particularly attenuated stress reactivity in high-anxious smokers. In addition, high-anxious smokers were expected to exhibit increased urges to smoke in response to stress.

methods115 smokers and 37 nonsmokers, aged 18-64 years, completed a laboratory session including mental stressors such as evaluated public speaking and mental arithmetic. Trait anxiety was assessed using Spielberger's State-Trait Anxiety Inventory. Cardiovascular autonomic indices, salivary cortisol, and the desire to smoke were measured at baseline, during stressors, and at recovery.

resultsRegression analyses showed that smokers exhibited attenuated cardiovascular stress responses in comparison to nonsmokers. Higher trait anxiety predicted attenuated systolic blood pressure responses to stress. No interaction effect of smoking status and trait anxiety was found in stress response measures. Higher trait anxiety predicted an increased desire to smoke in response to stress among smokers.

conclusionResults indicate that both smoking status and trait anxiety are associated with blunted sympatho-adrenal cardiovascular stress reactivity. Elevated urges to smoke in response to stress found among smokers with high trait anxiety suggest an important role of anxiety in smoking propensity and relapse.

Indexed as

AnxietyAdolescentAdultBlood PressureHumansHydrocortisoneMiddle AgedSmokingStress, PsychologicalYoung AdultHydrocortisonecardiovascular systemChronic smokingmental stresspsychophysiologysympathetic nervous systemtrait anxiety

Identifiers

PMID27484702
PMCPMC5055449

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.