Evidence map›Paper›PMID 27484499›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2017

Safety and efficacy in ablation of premature ventricular contraction: data from the German ablation registry.

S Fichtner, J Senges, M Hochadel, R Tilz, S Willems, L Eckardt, T Deneke, T Lewalter, U Dorwarth, C Reithmann and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. First in-human results of the MAGiC robotic magnetic navigation radiofrequency ablation catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
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  7. Real-world assessment of multipolar and point-by-point mapping for premature ventricular contraction ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
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  9. Twenty-five years of catheter ablation of ventricular tachycardia: a look back and a look forward.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
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  12. Efficacy of radiofrequency catheter ablation for premature ventricular contractions in children.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

S FichtnerKlinikum der LMU München, Medizinische Klinik und Poliklinik I, Deutsches Zentrum für Herz-Kreislauferkrankungen (DZHK), partner site Munich Heart Alliance, Marchioninistr. 15, 81377, Munich, Germany. Stephanie.fichtner@med.uni-muenchen.de.ORCID http://orcid.org/0000-0003-4100-6292
J SengesStiftung Institut für Herzinfarktforschung (IHF), Ludwigshafen, Germany.
M HochadelStiftung Institut für Herzinfarktforschung (IHF), Ludwigshafen, Germany.
R TilzUniversitätsklinikum Schleswig-Holstein, Lübeck, Germany.
S WillemsUniversitätsklinik Hamburg-Eppendorf, Hamburg, Germany.
L EckardtUniversitätsklinikum Münster, Münster, Germany.
T DenekeHerz- und Gefäßklinik Bad Neustadt, Bad Neustadt, Germany.
T LewalterPeter Osypka Herzzentrum, Internistische Klinik Dr. Müller, Munich, Germany.
U DorwarthKlinikum München-Bogenhausen, Munich, Germany.
C ReithmannHelios Klinikum München-West, Munich, Germany.
J BrachmannKlinikum Coburg, Coburg, Germany.
G SteinbeckZentrum für Kardiologie am Klinikum Starnberg, Starnberg, Germany.
S KääbKlinikum der LMU München, Medizinische Klinik und Poliklinik I, Deutsches Zentrum für Herz-Kreislauferkrankungen (DZHK), partner site Munich Heart Alliance, Marchioninistr. 15, 81377, Munich, Germany.
German Ablation Registry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with frequent premature ventricular contractions (PVCs) are often highly symptomatic with significantly reduced quality-of-life. We evaluated the outcome and success of PVC ablation in patients in the German Ablation Registry.

methodsThe German Ablation Registry is a nationwide prospective multicenter database of patients who underwent an ablation procedure, initiated by the "Stiftung Institut für Herzinfarktforschung" (IHF), Ludwigshafen, Germany. Data were acquired from March 2007 to May 2011. Patients underwent PVC ablation in the enrolling ablation centers.

resultsA total of 408 patients (age 53.5 ± 15 years, 55 % female) undergoing ablation for PVCs were included. 32 % of patients showed a co-existing structural heart disease. Acute ablation success of the procedure was 82 % in the overall patient group. In patients without structural heart disease, acute success was significantly higher compared with patients with structural heart disease (86 vs. 74 %, p = 0.002). All patients were discharged alive after a median of 3 days. No patient suffered an acute myocardial infarction, stroke, or major bleeding. After 12 months' follow-up, 99 % of patients were still alive showing a significant different mortality between patients with structural heart disease compared with those without (2.3 vs. 0 %, p = 0.012). In addition, 76 % of patients showed significantly improved symptoms after 12 months of follow-up.

conclusionBased on the data from this registry, ablation of PVCs is a safe and efficient procedure with an excellent outcome and improved symptoms after 12 months.

Indexed as

Catheter AblationAdultAgedElectrocardiographyFemaleGermanyHumansKaplan-Meier EstimateMaleMiddle AgedPostoperative ComplicationsRegistriesRisk FactorsTime FactorsTreatment OutcomeVentricular Premature ComplexesAblationLeft ventricular outflow tractPremature ventricular contractionPVCRegistryRight ventricular outflow tract

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.