Evidence map›Paper›PMID 27484472›Full record

ArticleJournal of cardiothoracic surgery2016

Outcomes following emergent open repair for thoracic aortic dissection are improved at higher volume centers in direct admissions and transfers.

Aurelie E Merlo, Dhaval Chauhan, Chris Pettit, Kimberly N Hong, Craig R Saunders, Chunguang Chen, Mark J Russo

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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  3. Review
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  5. The optimal annual case volume for acute type A aortic dissection surgery in relation to long-term outcomes.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
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  12. How should we manage type A aortic dissection?General thoracic and cardiovascular surgery · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Aurelie E MerloCardiovascular Clinical Research Unit, Barnabas Heart Hospitals, Newark, NJ, USA.
Dhaval ChauhanCardiovascular Clinical Research Unit, Barnabas Heart Hospitals, Newark, NJ, USA. dhavalchauhan86@gmail.com.
Chris PettitCardiovascular Clinical Research Unit, Barnabas Heart Hospitals, Newark, NJ, USA.
Kimberly N HongDepartment of Health Evidence and Policy, Mount Sinai School of Medicine, New York, NY, USA.
Craig R SaundersNewark Beth Israel Medical Center, Barnabas Heart Hospitals, Newark, NJ, USA.
Chunguang ChenNewark Beth Israel Medical Center, Barnabas Heart Hospitals, Newark, NJ, USA.
Mark J RussoCardiovascular Clinical Research Unit, Barnabas Heart Hospitals, Newark, NJ, USA.
Newark Beth Israel Medical Center · USHeart Foundation · USCase Western Reserve University · USIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study is (1) to define the proportion of patients undergoing emergent open repair of thoracic aortic dissection admitted directly through the emergency room versus those transferred from outside hospitals and (2) to determine if a volume-outcomes relationship exists for those patients across admission types.

methodsDe-identified patient-level data was obtained from the Nationwide Inpatient Sample (2004-2008). Patients undergoing emergent aortic surgery for thoracic aortic dissection (n = 1,507) were identified by ICD-9 codes and stratified by annual center volume into low volume (≤5 cases/year) (n = 963; 63.9 %), intermediate volume (6-10 cases/year) (n = 370; 24.5 %), and high volume (≥11 cases/year) (n = 174; 11.6 %) groups. The analysis was further stratified by admission type: direct admission (DA), transfer admission (TA), and other. The primary outcome was in-hospital mortality. Multivariate logistic regression analysis was performed comparing outcomes between high vs low and high vs intermediate volume centers.

resultsOverall in-hospital mortality was 21.8 % (n = 328/1,507). Absolute percent mortality at high volume centers was significantly lower (12.6 %) than at medium (20.6 %) and low volume (23.9 %) centers. For DA patients, mortality was 10.6, 21.4, and 24.0 % for high, medium, and low volume centers respectively. For TA patients, mortality was 10.2, 12.7, and 23.5 % for high, medium, and low volume centers, respectively. Multivariate analysis suggested that patients in low volume center were more likely to die compared to high volume center (Odds Ratio 2.06, 95 % CI 1.25 - 3.38, p = 0.004). Admission source was not associated with increased mortality.

conclusionsDirect admissions comprise the largest proportion of dissections regardless of volume strata, and they comprise the largest proportion in the low and intermediate volume cohorts. Admission to low volume center is an independent risk factor for increased mortality. Patients transferred to high volume centers from low volume centers have similar outcome as direct admits in terms of mortality.

Indexed as

AdultAgedAortic Aneurysm, ThoracicAortic DissectionFemaleHospitalizationHospital MortalityHumansMaleMiddle AgedPatient AdmissionPatient TransferRisk FactorsTreatment OutcomeUnited States

Identifiers

PMID27484472
PMCPMC4969670
OpenAlexW2503885276

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.