ReviewCurrent psychiatry reports2016
Early Childhood Environment and Genetic Interactions: the Diathesis for Suicidal Behavior.
Review in Current psychiatry reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The developmental origins of suicide mortality: a systematic review of longitudinal studies.European child & adolescent psychiatry · 2024Pooled it
- Commercially Sexually Exploited Adolescent Girls: The Association Between Externalizing Disorders and Parental Incarceration with Suicide Attempts.Child psychiatry and human development · 2026Article
- Beyond mental disorders: The role of child maltreatment in childhood suicidal behaviour.The Australian and New Zealand journal of psychiatry · 2026Article
- Polygenic Risk, Trait Variables, and External Stressors in Fatal and Nonfatal Suicidal Behavior.JAMA network open · 2026Article
- How left-behind experience moderates the impact of impulsivity on non-suicidal self-injury among Chinese senior high school students: the mediating role of self-control.Frontiers in public health · 2026Article
- Childhood trauma and suicidal behavior risk: perceived burdensomeness and negative emotional reactivity in a cross-sectional study.Frontiers in psychology · 2026Article
- Emotion Dysregulation, Impulsivity, and Implicit Cognition in Adolescent with Self-Injurious Thoughts and Behaviors: A Six-Month Prospective Study.Journal of clinical medicine · 2025Article
- Review
- The roles of adverse childhood experiences and genetic liability in risk for suicidal thoughts and behaviors: A factor analytic approach.Journal of affective disorders · 2025Article
- Lifetime stressor exposure is related to suicidality in autistic adults: A multinational study.Autism : the international journal of research and practice · 2025Article
- Longitudinal relation between negative life events and non-suicidal self-injury among Chinese college students: a moderated mediation model.BMC psychiatry · 2025Article
- [Interaction betweenZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Childhood maltreatment associated suicidal risk in Chinese children and adolescents: a mediation of resilience.BMC public health · 2024Article
- Article
- Middle school students' psychological health on suicide ideation: based on latent profile analysis.Frontiers in public health · 2024Article
- Article
- Adverse childhood experiences as a risk factor for non-suicidal self-injury and suicide attempts in forensic psychiatric patients.BMC psychiatry · 2023Article
- Non-suicidal self-injury and suicidal ideation among adolescents: the chain-mediating role of rumination and decentering.Frontiers in psychiatry · 2023Article
- Suicidal ideation during adolescence: The roles of aggregate genetic liability for suicide attempts and negative life events in the past year.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- Association Between Discrimination Stress and Suicidality in Preadolescent Children.Journal of the American Academy of Child and Adolescent Psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adverse childhood experiences are associated with higher risk for suicide and suicidal behavior later in life. There are known associations between childhood trauma, particularly sexual abuse, and higher rates of suicide, non-lethal suicide attempts, and non-suicidal self-injurious behaviors in adolescence and adulthood. Emotional abuse/neglect, disrupted parental attachment, and cumulative effect of multiple forms of maltreatment, also increase risk. Yet, the causal relationship remains unclear. The diathesis-stress model provides a framework for understanding how early life adverse experiences contribute to suicide vulnerability. Current findings from the fields of biology, neurology, and genetics shed new light on mediating variables and possible causal links between early childhood trauma and suicide. In this paper, we review recent advances, particularly regarding the interaction of early life environmental adverse events with genetics factors, that increase the diathesis for psychological traits are associated with subsequent deliberate self-harm behaviors.
Indexed as
Identifiers
27484207What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.