Evidence map›Paper›PMID 27483488›Full record

ArticleBlood transfusion = Trasfusione del sangue2017

Hepatitis E virus infections in travellers: assessing the threat to the Australian blood supply.

Ashish C Shrestha, Robert L P Flower, Clive R Seed, Anthony J Keller, Veronica Hoad, Robert Harley, Robyn Leader, Ben Polkinghorne, Catriona Furlong, Helen M Faddy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ashish C ShresthaResearch and Development, Australian Red Cross Blood Service, Kelvin Grove, QLD, Australia.
Robert L P FlowerResearch and Development, Australian Red Cross Blood Service, Kelvin Grove, QLD, Australia.
Clive R SeedMedical Services, Australian Red Cross Blood Service, Perth, WA, Australia.
Anthony J KellerMedical Services, Australian Red Cross Blood Service, Perth, WA, Australia.
Veronica HoadMedical Services, Australian Red Cross Blood Service, Perth, WA, Australia.
Robert HarleyMedical Services, Australian Red Cross Blood Service, Kelvin Grove, QLD, Australia.
Robyn LeaderOzFoodNet, Office of Health Protection, Australian Government Department of Health, Canberra, Australia.
Ben PolkinghorneOzFoodNet, Office of Health Protection, Australian Government Department of Health, Canberra, Australia.
Catriona FurlongOzFoodNet, New South Wales Department of Health, Sydney, Australia.
Helen M FaddyResearch and Development, Australian Red Cross Blood Service, Kelvin Grove, QLD, Australia.
Australian Red Cross Lifeblood · AUAustralian Government · AUThe University of Queensland · AUNew South Wales Department of Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn many developed countries hepatitis E virus (HEV) infections have occurred predominantly in travellers to countries endemic for HEV. HEV is a potential threat to blood safety as the virus is transfusion-transmissible. To minimise this risk in Australia, individuals diagnosed with HEV are deferred. Malarialdeferrals, when donors are restricted from donating fresh blood components following travel toanareain which malaria is endemic, probably also decrease the HEV risk, by deferring donors who travel to many countries also endemic for HEV. The aim of this study is to describe overseas-acquired HEV cases in Australia, in order to determine whether infection in travellers poses a risk to Australian blood safety. MATERIALS AND

methodsDetails of all notified HEV cases in Australia from 2002 to 2014 were accessed, and importation rates estimated. Countries in which HEV was acquired were compared to those for which donations are restricted following travel because of a malaria risk.

resultsThree hundred and thirty-two cases of HEV were acquired overseas. Travel to India accounted for most of these infections, although the importation rate was highest for Nepal and Bangladesh. Countries for which donations are restricted following travel due to malaria risk accounted for 94% of overseas-acquired HEV cases. DISCUSSION: The vast majority of overseas-acquired HEV infections were in travellers returning from South Asian countries, which are subject to donation-related travel restrictions for malaria. This minimises the risk HEV poses to the Australian blood supply.

Indexed as

AdolescentAdultAgedAsiaAustraliaBlood DonorsBlood SafetyCommunicable Diseases, ImportedFemaleHepatitis EHepatitis E virusHumansMaleMiddle AgedTravelYoung Adult

Identifiers

PMID27483488
PMCPMC5448823
OpenAlexW2513129270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.