Evidence map›Paper›PMID 27483445›Full record

ArticlePLoS biology2016

Ethics Reporting in Biospecimen and Genetic Research: Current Practice and Suggestions for Changes.

William Wei Lim Chin, Susanne Wieschowski, Jana Prokein, Thomas Illig, Daniel Strech

Abstract read
In one paragraph

Article in PLoS biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William Wei Lim ChinInstitute for History, Ethics, and Philosophy of Medicine, Hannover Medical School, Hannover, Germany.
Susanne WieschowskiInstitute for History, Ethics, and Philosophy of Medicine, Hannover Medical School, Hannover, Germany.
Jana ProkeinHannover Unified Biobank, Hannover Medical School, Hannover, Germany.
Thomas IlligHannover Unified Biobank, Hannover Medical School, Hannover, Germany.
Daniel StrechInstitute for History, Ethics, and Philosophy of Medicine, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-9153-079X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern approaches for research with human biospecimens employ a variety of substantially different types of ethics approval and informed consent. In most cases, standard ethics reporting such as "consent and approval was obtained" is no longer meaningful. A structured analysis of 120 biospecimen studies recently published in top journals revealed that more than 85% reported on consent and approval, but in more than 90% of cases, this reporting was insufficient and thus potentially misleading. Editorial policies, reporting guidelines, and material transfer agreements should include recommendations for meaningful ethics reporting in biospecimen research. Meaningful ethics reporting is possible without higher word counts and could support public trust as well as networked research.

Indexed as

Biological Specimen BanksEditorial PoliciesGenetic ResearchHumansInformed ConsentPublishingResearch ReportTrust

Identifiers

PMID27483445
PMCPMC4970810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.