Trial reportNutrients2016
Associations of Fat Mass and Fat-Free Mass with Physical Fitness in 4-Year-Old Children: Results from the MINISTOP Trial.
Trial report in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Sex Differences in Grip Strength From Birth to Age 16: A Meta-Analysis.European journal of sport science · 2025Pooled it
- Body composition, physical fitness and cardiovascular risk factors in 9-year-old children.Scientific reports · 2022Trial
- Parental body mass index and its association with body composition, physical fitness and lifestyle factors in their 4-year-old children: results from the MINISTOP trial.European journal of clinical nutrition · 2017Trial
- Validation of Body Surface Area Equations for Estimating Fat-Free Mass by Dual X-Ray Absorptiometry in a Regional Chilean Sample Aged 4 to 85 Years.Diagnostics (Basel, Switzerland) · 2025Article
- Body Composition and Its Correlates in Children and Adolescents Living in Germany: A Cross-Sectional Study.European journal of sport science · 2025Article
- Physical fitness is associated with fat mass and muscle mass in Chinese preschoolers.BMC public health · 2025Article
- Reallocation of time to moderate-to-vigorous physical activity and estimated changes in physical fitness among preschoolers: a compositional data analysis.BMC public health · 2024Article
- Longitudinal Relationships of Physical Activity, Sedentary Time, Cardiorespiratory Fitness, and Muscular Fitness with Body Fatness in Preschoolers.Sports (Basel, Switzerland) · 2024Article
- Evaluation of physical fitness and health of young children aged between 3 and 6 based on cluster and factor analyses.BMC public health · 2024Article
- The relative contributions of soft tissue mass components as risk or protective factors of non-alcoholic fatty liver disease in children.European journal of clinical nutrition · 2023Article
- Associations between basic motor competencies and physical fitness in Spanish pre-schoolers: a cross-sectional study.Italian journal of pediatrics · 2023Article
- The relationship between physical activity, physical fitness and fatness in 3-6 years old boys and girls: a cross-sectional study.Translational pediatrics · 2022Article
- Study of the Reliability of Field Test Methods for Physical Fitness in Children Aged 2-3 Years.International journal of environmental research and public health · 2022Article
- Associations between Fat Mass and Fat Free Mass with Physical Fitness in Adolescent Girls: A 3-Year Longitudinal Study.Biology · 2022Article
- Associations Between Fitness, Physical Activity, and Fatness in Preschool Children With Typical and Atypical Motor Coordination.Frontiers in pediatrics · 2022Article
- Field-based physical fitness assessment in preschool children: A scoping review.Frontiers in pediatrics · 2022Article
- Article
- Association of Body Compositions and Bone Mineral Density in Chinese Children and Adolescents: Compositional Data Analysis.BioMed research international · 2021Article
- Secular Changes in Body Build and Body Composition in Czech Preschool Children in the Context of Latent Obesity.Children (Basel, Switzerland) · 2020Article
- DNA methylation in infants with low and high body fatness.BMC genomics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical fitness is a powerful marker of health in youth. Studies in adolescents and adults suggest that higher fat mass is related to worse physical fitness. However, there is limited knowledge whether fat mass and fat-free mass are associated with physical fitness already in preschoolers. Baseline data from the MINISTOP (Mobile-based INtervention Intended to STop Obesity in Preschoolers) trial was utilized for this cross-sectional analysis. Body composition was assessed using air-displacement plethysmography. Fat mass index [fat mass (kg)/height² (m)] and fat-free mass index [fat-free mass (kg)/height² (m)] were used to provide height-adjusted measures of body composition. Physical fitness was measured using the PREFIT (FITness testing in PREschool children) battery, which assesses cardiorespiratory fitness, upper-body and lower-body muscular strength as well as motor fitness. In total, this study included 303 children (168 boys and 135 girls), who were on average 4.48 ± 0.15 years old. Higher fat mass index was associated with worse cardiorespiratory fitness (standardized β = -0.17, p = 0.002), lower-body muscular strength (β = -0.17, p = 0.003) and motor fitness (β = -0.21, p < 0.001) in regression analyses adjusted for age, sex and mutually adjusted for fat-mass index and fat-free mass index. Conversely, higher fat-free mass index was associated with better cardiorespiratory fitness (β = 0.18, p = 0.002), upper-body muscular strength (β = 0.39, p < 0.001), lower-body muscular strength (β = 0.22, p < 0.001) and motor fitness (β = 0.17, p = 0.004). Thus, fat mass and fat-free mass in preschoolers appear to have joint but opposite associations with physical fitness, an important marker for current and future health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.