ReviewInternational journal of environmental research and public health2016
Endocrine Aspects of Environmental "Obesogen" Pollutants.
Review in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Long-Term Outcomes in Sleeve Gastrectomy versus Roux-en-Y Gastric Bypass: A Systematic Review and Meta-Analysis of Randomized Trials.Obesity surgery · 2025Pooled it
- Inhibitory control mediates the association between perinatal PM2.5 exposure and childhood obesity in children in the PROGRESS cohort, Mexico City.Communications medicine · 2026Article
- Soil health to human health: impacts of soil contaminants on cardio-neurological health and clinical outcomes: a narrative review.Frontiers in cardiovascular medicine · 2026Review
- Trends in lifestyle and mental health among 0.1 million Chinese: a longitudinal study pre- and post-COVID-19.International health · 2025Article
- Obesity and obesity related disease in adulthood: the dark side of early life exposure to Environmental Chemical Disruptors.Journal of endocrinological investigation · 2025Review
- Tetramethyl Bisphenol F: Organ- and System-Specific Toxicity, Current Status, and Perspectives.International journal of molecular sciences · 2025Review
- Association between World Trade Center disaster exposures and body mass index in community members enrolled at World Trade Center Environmental Health Center.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Protective effects of resveratrol and naringenin against nonylphenol-induced oxidative stress in rats.AMB Express · 2025Article
- Associations of early life per- and polyfluoroalkyl substances (PFAS) exposure with body mass index and risk of overweight or obesity at age 2-18 years: Mixture analysis in the prospective Boston Birth Cohort.Environment international · 2025Article
- Bridging east and west: integrative approaches to obesity management through traditional Chinese medicine.Frontiers in endocrinology · 2025Review
- Sex-specific associations between the environmental exposures and low-grade inflammation and increased blood pressure in young, healthy subjects.Scientific reports · 2024Article
- [Synthetic phenolic compounds perturb lipid metabolism and induce obesogenic effects].Se pu = Chinese journal of chromatography · 2024Review
- From a toxin to an obesogen: a review of potential obesogenic roles of acrylamide with a mechanistic approach.Nutrition reviews · 2023Review
- Nonylphenol Exposure-Induced Oocyte Quality Deterioration Could be Reversed by Boric Acid Supplementation in Rats.Biological trace element research · 2023Article
- Causes of obesity: a review.Clinical medicine (London, England) · 2023Review
- Associations of Gestational Perfluoroalkyl Substances Exposure with Early Childhood BMIEnvironmental health perspectives · 2023Article
- Application of In Vitro Models for Studying the Mechanisms Underlying the Obesogenic Action of Endocrine-Disrupting Chemicals (EDCs) as Food Contaminants-A Review.International journal of molecular sciences · 2023Review
- Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats.Frontiers in endocrinology · 2023Article
- Ozone modified hypothalamic signaling enhancing thermogenesis in the TDP-43Scientific reports · 2022Article
- Association between dietary exposure to bisphenols and body mass index in Spanish schoolchildren.EFSA journal. European Food Safety Authority · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growing evidence suggests the causal link between the endocrine-disrupting chemicals (EDCs) and the global obesity epidemics, in the context in the so-called "obesogenic environment". Dietary intake of contaminated foods and water, especially in association with unhealthy eating pattern, and inhalation of airborne pollutants represent the major sources of human exposure to EDCs. This is of particular concern in view of the potential impact of obesity on chronic non-transmissible diseases, such as type 2 diabetes, cardiovascular disease, and hormone-sensitive cancers. The key concept is the identification of adipose tissue not only as a preferential site of storage of EDCs, but also as an endocrine organ and, as such, susceptible to endocrine disruption. The timing of exposure to EDCs is critical to the outcome of that exposure, with early lifetime exposures (e.g., fetal or early postnatal) particularly detrimental because of their permanent effects on obesity later in life. Despite that the mechanisms operating in EDCs effects might vary enormously, this minireview is aimed to provide a general overview on the possible association between the pandemics of obesity and EDCs, briefly describing the endocrine mechanisms linking EDCs exposure and latent onset of obesity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.