ArticlePloS one2016
The Yield of Community-Based "Retrospective" Tuberculosis Contact Investigation in a High Burden Setting in Ethiopia.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Facilitators and barriers to tuberculosis active case findings in low- and middle-income countries: a systematic review of qualitative research.BMC infectious diseases · 2023Pooled it
- Effectiveness of contact tracing in the control of infectious diseases: a systematic review.The Lancet. Public health · 2022Pooled it
- Screening tests for active pulmonary tuberculosis in children.The Cochrane database of systematic reviews · 2021Pooled it
- Molecular epidemiology of M. tuberculosis in Ethiopia: A systematic review and meta-analysis.Tuberculosis (Edinburgh, Scotland) · 2019Pooled it
- Article
- Epidemiology of active tuberculosis among adult household contacts of patients with smear-positive pulmonary tuberculosis in Kembata-Tembaro zone, southern Ethiopia: a cross-sectional study.BMJ public health · 2025Article
- Household drug-resistant TB contact tracing in Tajikistan.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023Article
- Household Contact Tuberculosis Screening Adherence and Associated Factors Among Pulmonary Tuberculosis Patients on Follow-Up at Health Facilities in Shashamane Town, Southeast Ethiopia.Patient preference and adherence · 2023Article
- Determinants of losses in the tuberculosis infection cascade of care among children and adolescent contacts of pulmonary tuberculosis cases: A Brazilian multi-centre longitudinal study.Lancet regional health. Americas · 2022Article
- Implementing active surveillance for tuberculosis: The experiences of healthcare workers at four sites in two provinces in South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022Article
- Evaluating the yield of systematic screening for tuberculosis among three priority groups in Ho Chi Minh City, Viet Nam.Infectious diseases of poverty · 2020Article
- Case finding strategies under National Tuberculosis Elimination Programme (NTEP).The Indian journal of tuberculosis · 2020Review
- Tuberculosis disease and infection among household contacts of bacteriologically confirmed and non-confirmed tuberculosis patients.Tropical medicine & international health : TM & IH · 2020Article
- Yield of household contact investigation of patients with pulmonary tuberculosis in southern Ethiopia.BMC public health · 2020Article
- Implementation status of household contact tuberculosis screening by health extension workers: assessment findings from programme implementation in Tigray region, northern Ethiopia.BMC health services research · 2020Article
- Article
- Prevalence and Associated Factors of Tuberculosis among Adult Household Contacts of Smear Positive Pulmonary Tuberculosis Patients Treated in Public Health Facilities of Haramaya District, Oromia Region, Eastern Ethiopia.Tuberculosis research and treatment · 2020Article
- Tuberculosis infectious pool and associated factors in East Gojjam Zone, Northwest Ethiopia.BMC pulmonary medicine · 2019Article
- 'Something so hard': a mixed-methods study of home sputum collection for tuberculosis contact investigation in Uganda.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018Article
- Yield of tuberculosis among household contacts of tuberculosis patients in Accra, Ghana.Infectious diseases of poverty · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the yield and determinants of retrospective TB contact investigation in selected zones in Ethiopia. MATERIALS AND
methodsThis was a community-based cross-sectional study conducted during June-October 2014.Trained lay providers performed symptom screening for close contacts of index cases with all types of TB registered for anti-TB treatment within the last three years. We used logistic regression to determine factors associated with TB diagnosis among the contacts.
resultsOf 272,441 close contacts of 47, 021 index cases screened, 13,886 and 2, 091 had presumptive and active TB respectively. The yield of active TB was thus 768/100, 000, contributing 25.4% of the 7,954 TB cases reported from the study zones over the study period. The yield was highest among workplace contacts (12,650/100, 000). Active TB was twice more likely among contacts whose index cases had been registered for TB treatment within the last 12 months compared with those who had been registered 24 or more months earlier (adjusted odds ratio, AOR: 1.77 95% CI 1.42-2.21). Sex or clinical type of TB in index cases was not associated with the yield. Smear negative (SS-) index cases (AOR: 1.74 955 CI 1.13-2.68), having index cases who registered for treatment within <12 months (AOR: 2.41 95% CI 1.51-3.84) and being household contact (AOR: 0.072 95% CI 0.01-0.52) were associated with the occurrence of active TB in children.
conclusionsThe yield of retrospective contact investigation was about six times the case notification in the study zones, contributing a fourth of all TB cases notified over the same period. The yield was highest among workplace contacts and in those with recent past history of contact. Retrospective contact screening can serve as additional strategy to identify high risk groups not addressed through currently recommended screening approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.