Evidence map›Paper›PMID 27482978›Full record

ArticleInflammatory bowel diseases2016

Impact of Specialized Inpatient IBD Care on Outcomes of IBD Hospitalizations: A Cohort Study.

Cindy C Y Law, Saranya Sasidharan, Rodrigo Rodrigues, Deanna D Nguyen, Jenny Sauk, John Garber, Cosmas Giallourakis, Ramnik Xavier, Hamed Khalili, Vijay Yajnik and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Inflammatory bowel diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
  4. Rate of Risk Factors for and Interventions to Reduce Hospital Readmission in Patients With Inflammatory Bowel Diseases.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
    Pooled it
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  18. Treating IBD? Don't Forget that Mental Health Matters.Digestive diseases and sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Cindy C Y Law*Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts; †University of Ottawa, Ottawa, Ontario, Canada; ‡Boston Medical Center, Boston, Massachusetts; §North Shore Community Health Center, Salem, Massachusetts; and ‖Harvard Medical School, Boston, Massachusetts.
Saranya Sasidharan
Rodrigo Rodrigues
Deanna D Nguyen
Jenny Sauk
John Garber
Cosmas Giallourakis
Ramnik Xavier
Hamed Khalili
Vijay Yajnik
Ashwin N Ananthakrishnan
Harvard University · USMassachusetts General Hospital · USBoston Medical Center · USCommunity Health Center · USUniversity of Ottawa · CA

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ANDREW D LUSTER · 1991 to 2026
$35.3M
Oral Contraceptives in the Etiopathogenesis of Crohn's DiseaseK23DK099681 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KHALILI, HAMED · 2013 to 2017
$946k
Genetic predictors of anti-TNF treatment response and infections in IBDK23DK097142 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ANANTHAKRISHNAN, ASHWIN N · 2012 to 2016
$846k
NIDDK NIH HHS K23 DK097142NIDDK NIH HHS K23 DK099681NIDDK NIH HHS P30 DK043351
6 · The paper itself

Abstract

backgroundThe management of inflammatory bowel diseases (IBDs; Crohn's disease, ulcerative colitis) is increasingly complex. Specialized care has been associated with improved ambulatory IBD outcomes.

aimsTo examine if the implementation of specialized inpatient IBD care modified short-term and long-term clinical outcomes in IBD-related hospitalizations.

methodsThis retrospective cohort study included IBD patients hospitalized between July 2013 and April 2015 at a single tertiary referral center where a specialized inpatient IBD care model was implemented in July 2014. In-hospital medical and surgical outcomes as well as postdischarge outcomes at 30 and 90 days were analyzed along with measures of quality of in-hospital care. Effect of specialist IBD care was examined on multivariate analysis.

resultsA total of 408 IBD-related admissions were included. With implementation of specialized IBD inpatient care, we observed increased frequency of use of high-dose biologic therapy for induction (26% versus 9%, odds ratio 5.50, 95% confidence interval 1.30-23.17) and higher proportion of patients in remission at 90 days after discharge (multivariate odds ratio 1.60, 95% confidence interval 0.99-2.69). Although there was no difference in surgery by 90 days, among those who underwent surgery, early surgery defined as in-hospital or within 30 days of discharge, was more common in the study period (71%) compared with the control period (46%, multivariate odds ratio 2.73, 95% confidence interval 1.22-6.12). There was no difference in length of stay between the 2 years.

conclusionsImplementation of specialized inpatient IBD care beneficially impacted remission and facilitated early surgical treatment.

Indexed as

Biological TherapyHospitalizationRemission InductionAdrenal Cortex HormonesAdultBostonDigestive System Surgical ProceduresFemaleHumansInflammatory Bowel DiseasesInpatientsLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisAdrenal Cortex Hormones

Identifiers

PMID27482978
PMCPMC4992425
OpenAlexW2336334645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.