Evidence map›Paper›PMID 27482893›Full record

Observational studyAIDS care2017

Not all non-drinkers with HIV are equal: demographic and clinical comparisons among current non-drinkers with and without a history of prior alcohol use disorders.

Heidi M Crane, Robin M Nance, Joseph O Merrill, Heidi Hutton, Geetanjali Chander, Mary E McCaul, W Chris Mathews, Rob Fredericksen, Jane M Simoni, Kenneth Mayer and 16 more

Open access · greenAbstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in AIDS care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 8 institutions in 1 country.

Heidi M Cranea Department of Medicine , University of Washington , Seattle , WA , USA.
Robin M Nancea Department of Medicine , University of Washington , Seattle , WA , USA.
Joseph O Merrilla Department of Medicine , University of Washington , Seattle , WA , USA.
Heidi Huttonb Department of Psychiatry and Behavioral Sciences , Johns Hopkins University , Baltimore , MD , USA.
Geetanjali Chanderc Department of Medicine , Johns Hopkins University , Baltimore , MD , USA.
Mary E McCaulb Department of Psychiatry and Behavioral Sciences , Johns Hopkins University , Baltimore , MD , USA.
W Chris Mathewsd Department of Medicine , University of California , San Diego , CA , USA.
Rob Fredericksena Department of Medicine , University of Washington , Seattle , WA , USA.
Jane M Simonie Department of Psychology , University of Washington , Seattle , WA , USA.
Kenneth Mayerf Fenway Institute and Department of Medicine , Harvard Medical School , Boston , MA , USA.
Michael J Mugaverog Department of Medicine , University of Alabama at Birmingham , Birmingham , AL , USA.
James H Willigg Department of Medicine , University of Alabama at Birmingham , Birmingham , AL , USA.
Greer Burkholderg Department of Medicine , University of Alabama at Birmingham , Birmingham , AL , USA.
Daniel R Drozda Department of Medicine , University of Washington , Seattle , WA , USA.
Matthew Mimiagah Departments of Behavioral and Social Sciences , Brown University , Providence , RI , USA.
Bryan Laui Department of Epidemiology , Johns Hopkins University , Baltimore , MD , USA.
H Nina Kima Department of Medicine , University of Washington , Seattle , WA , USA.
Karen Cropseyj Department of Psychiatry , University of Alabama at Birmingham , Birmingham , AL , USA.
Richard D Moorec Department of Medicine , Johns Hopkins University , Baltimore , MD , USA.
Katerina Christopoulosk Department of Medicine , University of California at San Francisco , San Francisco , CA , USA.
Elvin Gengk Department of Medicine , University of California at San Francisco , San Francisco , CA , USA.
Joseph J Eronl Department of Medicine , University of North Carolina , Chapel Hill , NC , USA.
Sonia Napravnikl Department of Medicine , University of North Carolina , Chapel Hill , NC , USA.
Mari M Kitahataa Department of Medicine , University of Washington , Seattle , WA , USA.
Michael S Saagg Department of Medicine , University of Alabama at Birmingham , Birmingham , AL , USA.
Joseph Ac Delaneym Department of Epidemiology , University of Washington , Seattle , WA , USA.
University of Washington · USJohns Hopkins University · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USUniversity of North Carolina at Chapel Hill · USBrown University · USFenway Health · USUniversity of California, San Diego · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Tribal College and Universities Behavioral Wellness Project (TCU BeWell)P60MD006909 · NIMHD · UNIVERSITY OF WASHINGTON · PI WALTERS, KARINA LYNN · 2012 to 2016
$6.3M
3/4 Alcohol Research Consortium in HIV - Epidemiological Research Arm (ARCH-ERA)U01AA020793 · NIAAA · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., LAU, BRYAN · 2011 to 2020
$5.8M
Integration of Evidence-based Alcohol Interventions into HIV CareU01AA020802 · NIAAA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CROPSEY, KAREN L, MUGAVERO, MICHAEL J · 2011 to 2020
$4.2M
The ITZA Program: Indigenous HIV/AIDS Research Training 3 (IHART3) ProgramR25MH084565 · NIMH · UNIVERSITY OF WASHINGTON · PI Teresa A Evans-Campbell, Michelle D Johnson-Jennings · 2009 to 2026
$3.7M
1/4 Alcohol Research Consortium in HIV-Administrative Core (ARCH-AC)U24AA020801 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI, MCCAUL, MARY E · 2011 to 2021
$3.5M
NIAAA NIH HHS U01 AA020793NIAAA NIH HHS U01 AA020802NIAAA NIH HHS U24 AA020801NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI050410NIAID NIH HHS R24 AI067039NIMHD NIH HHS P60 MD006909NIMH NIH HHS R25 MH084565
6 · The paper itself

Abstract

Studies of persons living with HIV (PLWH) have compared current non-drinkers to at-risk drinkers without differentiating whether current non-drinkers had a prior alcohol use disorder (AUD). The purpose of this study was to compare current non-drinkers with and without a prior AUD on demographic and clinical characteristics to understand the impact of combining them. We included data from six sites across the US from 1/2013 to 3/2015. Patients completed tablet-based clinical assessments at routine clinic appointments using the most recent assessment. Current non-drinkers were identified by AUDIT-C scores of 0. We identified a prior probable AUD by a prior AUD diagnosis in the electronic medical record (EMR) or a report of attendance at alcohol treatment in the clinical assessment. We used multivariate logistic regression to examine factors associated with prior AUD. Among 2235 PLWH who were current non-drinkers, 36% had a prior AUD with more patients with an AUD identified by the clinical assessment than the EMR. Higher proportions with a prior AUD were male, depressed, and reported current drug use compared to non-drinkers without a prior AUD. Former cocaine/crack (70% vs. 25%), methamphetamine/crystal (49% vs. 16%), and opioid/heroin use (35% vs. 7%) were more commonly reported by those with a prior AUD. In adjusted analyses, male sex, past methamphetamine/crystal use, past marijuana use, past opioid/heroin use, past and current cocaine/crack use, and cigarette use were associated with a prior AUD. In conclusion, this study found that among non-drinking PLWH in routine clinical care, 36% had a prior AUD. We found key differences between those with and without prior AUD in demographic and clinical characteristics, including drug use and depression. These results suggest that non-drinkers are heterogeneous and need further differentiation in studies and that prior alcohol misuse (including alcohol treatment) should be included in behavioural health assessments as part of clinical care.

Indexed as

AdultAlcohol DrinkingAlcohol-Related DisordersAmphetamine-Related DisordersCocaine-Related DisordersDemographyElectronic Health RecordsFemaleHIV InfectionsHumansLongitudinal StudiesMaleMarijuana AbuseMiddle AgedOpioid-Related DisordersSex Factorsadherencealcohol usealcohol use disordersHIVsubstance use

Identifiers

PMID27482893
PMCPMC5628736
OpenAlexW2482046579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.