SynthesisPloS one2016
Reported Outcome Measures in Degenerative Cervical Myelopathy: A Systematic Review.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04631471 (Regeneration in Cervical Degenerative Myelopathy - a Multi-centre, Double-blind, Randomised, Placebo Controlled Trial Assessing the Efficacy of Ibudilast as an Adjuvant Treatment to Decompressive Surgery for Degenerative Cervical Myelopathy), which is not on this map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Regeneration in Cervical Degenerative Myelopathy - a Multi-centre, Double-blind, Randomised, Placebo Controlled Trial Assessing the Efficacy of Ibudilast as an Adjuvant Treatment to Decompressive Surgery for Degenerative Cervical Myelopathy
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Reported outcomes in transsphenoidal surgery for pituitary adenomas: a systematic review.Pituitary · 2023Pooled it
- Pooled it
- The reporting of study and population characteristics in degenerative cervical myelopathy: A systematic review.PloS one · 2017Pooled it
- Characterizing proprioceptive dysfunction as an early sensory indicator of mild Degenerative Cervical Myelopathy.North American Spine Society journal · 2026Article
- Understanding degenerative cervical myelopathy in musculoskeletal practice.The Journal of manual & manipulative therapy · 2025Review
- A minimum data set-Core outcome set, core data elements, and core measurement set-For degenerative cervical myelopathy research (AO Spine RECODE DCM): A consensus study.PLoS medicine · 2024Article
- Machine Learning and Symptom Patterns in Degenerative Cervical Myelopathy: Web-Based Survey Study.JMIR formative research · 2024Article
- Relationship between disability and physical activity frequency after cervical spine surgery: A linear mixed model analysis.Journal of back and musculoskeletal rehabilitation · 2024Article
- Rapidly Deteriorating Degenerative Cervical Myelopathy Following Ventricular Shunt Revision for Hydrocephalus: Case Report.Interactive journal of medical research · 2023Article
- Life expectancy in patients with degenerative cervical myelopathy is currently reduced but can be restored with timely treatment.Acta neurochirurgica · 2023Observational
- Diffusion basis spectrum imaging predicts long-term clinical outcomes following surgery in cervical spondylotic myelopathy.The spine journal : official journal of the North American Spine Society · 2023Article
- Answer to the letter to the editor of A. Lawson McLean, et al. concerning "myelopathy disability index: establishing criteria for mild, moderate and severe impairment in patients with degenerative cervical myelopathy" by Pons Carreto A et al. (Eur Spine J; 2023: doi:10.1007/s00586-022-07506-2).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Article
- Targeting earlier diagnosis: What symptoms come first in Degenerative Cervical Myelopathy?PloS one · 2023Article
- Article
- Clinical and Research MRI Techniques for Assessing Spinal Cord Integrity in Degenerative Cervical Myelopathy-A Scoping Review.Biomedicines · 2022Article
- Moving Beyond the Neck and Arm: The Pain Experience of People With Degenerative Cervical Myelopathy Who Have Pain.Global spine journal · 2022Article
- Existing Funding Sources in Degenerative Cervical Myelopathy Research: Scoping Review.Interactive journal of medical research · 2022Article
- Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS).BMJ open · 2022Article
- Provision and Perception of Physiotherapy in the Nonoperative Management of Degenerative Cervical Myelopathy (DCM): A Cross-Sectional Questionnaire of People Living With DCM.Global spine journal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveDegenerative cervical myelopathy [DCM] is a disabling and increasingly prevalent group of diseases. Heterogeneous reporting of trial outcomes limits effective inter-study comparison and optimisation of treatment. This is recognised in many fields of healthcare research. The present study aims to assess the heterogeneity of outcome reporting in DCM as the premise for the development of a standardised reporting set.
methodsA systematic review of MEDLINE and EMBASE databases, registered with PROSPERO (CRD42015025497) was conducted in accordance with PRISMA guidelines. Full text articles in English, with >50 patients (prospective) or >200 patients (retrospective), reporting outcomes of DCM were eligible.
results108 studies, assessing 23,876 patients, conducted world-wide, were identified. Reported outcome themes included function (reported by 97, 90% of studies), complications (reported by 56, 52% of studies), quality of life (reported by 31, 29% of studies), pain (reported by 29, 27% of studies) and imaging (reported by 59, 55% of studies). Only 7 (6%) studies considered all of domains in a single publication. All domains showed variability in reporting.
conclusionsSignificant heterogeneity exists in the reporting of outcomes in DCM. The development of a consensus minimum dataset will facilitate future research synthesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.