Evidence map›Paper›PMID 27482531›Full record

ArticleAnnual review of statistics and its application2016

Statistical Methods in Integrative Genomics.

Sylvia Richardson, George C Tseng, Wei Sun

Abstract read
In one paragraph

Article in Annual review of statistics and its application, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Statistical genomics in rare cancer.Seminars in cancer biology · 2020
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. The role of double heterozygotes of SLC3A1 and SLC7A9 in the prevalence of cystine stones.Genetics in medicine : official journal of the American College of Medical Genetics · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Generalized Liquid Association Analysis for Multimodal Data Integration.Journal of the American Statistical Association · 2023
    Article
  18. Orthogonalized Kernel Debiased Machine Learning for Multimodal Data Analysis.Journal of the American Statistical Association · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sylvia RichardsonMRC Biostatistics Unit, Cambridge Institute of Public Health, University of Cambridge, CB2 0SR, United Kingdom.
George C TsengDepartment of Biostatistics, University of Pittsburgh, Pittsburgh, PA 15261.
Wei SunDepartment of Biostatistics, Department of Genetics, University of North Carolina, Chapel Hill, NC 27599; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 27516.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
Statistical Methods for RNA-seq Data AnalysisR01GM105785 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wei Sun · 2014 to 2026
$4.6M
Power calculation and design issues in next-generation sequencingR01CA190766 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TSENG, GEORGE C. · 2015 to 2018
$876k
Medical Research Council MC_UP_0801/1Medical Research Council MC_UU_00002/10NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA190766NIGMS NIH HHS R01 GM105785
6 · The paper itself

Abstract

Statistical methods in integrative genomics aim to answer important biology questions by jointly analyzing multiple types of genomic data (vertical integration) or aggregating the same type of data across multiple studies (horizontal integration). In this article, we introduce different types of genomic data and data resources, and then review statistical methods of integrative genomics, with emphasis on the motivation and rationale of these methods. We conclude with some summary points and future research directions.

Indexed as

genomicshorizontal data integrationintegrative genomicsvertical data integration

Identifiers

PMID27482531
PMCPMC4963036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.