Evidence map›Paper›PMID 27482442›Full record

ArticleJournal of virus eradication2016

Factors associated with HIV viral load suppression on antiretroviral therapy in Vietnam.

Suresh Rangarajan, J Colby Donn, Le Truong Giang, Duc Duong Bui, Huu Hung Nguyen, Plui Broh Tou, Tran Tri Danh, Ngoc Bao Chau Tran, Duc Anh Nguyen, Bao Tram Hoang Nguyen and 11 more

Abstract read
In one paragraph

Article in Journal of virus eradication, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it.

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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Suresh RangarajanFHI 360 , Ho Chi Minh City , Vietnam.
J Colby DonnSEARCH, Thai Red Cross AIDS Research Center, Bangkok, Thailand; Center for Applied Research on Men and Health, Ho Chi Minh City, Vietnam.
Le Truong GiangHo Chi Minh City Provincial AIDS Committee , Ho Chi Minh City , Vietnam.
Duc Duong BuiVietnam Administration for AIDS Control , Hanoi , Vietnam.
Huu Hung NguyenHo Chi Minh City Provincial AIDS Committee , Ho Chi Minh City , Vietnam.
Plui Broh TouFHI 360 , Ho Chi Minh City , Vietnam.
Tran Tri DanhFHI 360 , Ho Chi Minh City , Vietnam.
Ngoc Bao Chau TranFHI 360 , Ho Chi Minh City , Vietnam.
Duc Anh NguyenFHI 360 , Hanoi , Vietnam.
Bao Tram Hoang NguyenFHI 360 , Ho Chi Minh City , Vietnam.
Vu Tuyet Nga DoanFHI 360 , Ho Chi Minh City , Vietnam.
Nhat Quang NguyenFHI 360 , Ho Chi Minh City , Vietnam.
Van Phuoc PhamFHI 360 , Ho Chi Minh City , Vietnam.
Duc Giang DaoFHI 360 , Hanoi , Vietnam.
Mario ChenFHI 360 , North Carolina , United States.
Yanwu ZengFHI 360 , North Carolina , United States.
Thi Thu Van TieuHo Chi Minh City Provincial AIDS Committee , Ho Chi Minh City , Vietnam.
My Hanh TranAn Giang Provincial AIDS Center , Long Xuyen , An Giang , Vietnam.
Thi Hoa LeQuang Ninh Provincial AIDS Center , Ha Long , Vietnam.
Xuan Chien HoangDien Bien Provincial AIDS Center , Dien Bien , Vietnam.
Gary WestFHI 360 (retired).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited data are available on HIV viral suppression rates among men and women on antiretroviral therapy (ART) and factors associated with HIV RNA viral load (VL) suppression in Vietnam.

methodsWe conducted a cross-sectional survey of 1255 adult patients on ART for at least 1 year across four provinces in Vietnam. Data collection included a standardised questionnaire, routine laboratory testing, and an HIV VL assay. Bivariate and logistic multivariate analyses were conducted to assess viral suppression rates and factors associated with unsuppressed HIV VL.

resultsThe median age was 34.5 years and the median time on ART was 46 months. Gender was 66% male (n=828) and 34% female (n=427). HIV viral suppression below 1000 copies/mL was 93%. Viral suppression among woman was not significantly different than among men (93.7% vs 92.9%; P=0.59). On multivariate analysis, unsuppressed HIV VL was independently associated with lower CD4 cell count, social isolation, high stigma, not receiving a single-tablet daily regimen, multiple late appointments in past year, and immunological failure.

conclusionOn-treatment viral load suppression rates in Vietnam are high and already exceed the UNAIDS 90% target for viral suppression on ART. Gender does not impact viral suppression rates of patients on ART in Vietnam. Access to routine viral load testing should be improved, adherence monitoring and counselling streamlined, and ART regimens simplified to maintain viral suppression rates, as more people start ART. Psychological and social factors are also associated with unsuppressed HIV VL, necessitating treatment support interventions to address social isolation and stigma among people living with HIV in Vietnam.

Indexed as

adherenceantiretroviral therapygenderHIVHIV viral load suppressionsingle-tablet regimenVietnam

Identifiers

PMID27482442
PMCPMC4965252

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.