Evidence map›Paper›PMID 27482379›Full record

ArticleArchives of public health = Archives belges de sante publique2016

The LifeLines Cohort Study: a resource providing new opportunities for environmental epidemiology.

Wilma L Zijlema, Nynke Smidt, Bart Klijs, David W Morley, John Gulliver, Kees de Hoogh, Salome Scholtens, Judith G M Rosmalen, Ronald P Stolk

Abstract read
In one paragraph

Article in Archives of public health = Archives belges de sante publique, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wilma L ZijlemaDepartment of Epidemiology, University Medical Center Groningen, HPC CC72, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Nynke SmidtDepartment of Epidemiology, University Medical Center Groningen, HPC CC72, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Bart KlijsDepartment of Epidemiology, University Medical Center Groningen, HPC CC72, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
David W MorleyDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
John GulliverDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.
Kees de HooghDepartment of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College London, London, UK ; Swiss Tropical and Public Health Institute, Basel, Switzerland ; University of Basel, Basel, Switzerland.
Salome ScholtensLifeLines Cohort Study, Groningen, The Netherlands.
Judith G M RosmalenDepartment of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ronald P StolkDepartment of Epidemiology, University Medical Center Groningen, HPC CC72, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands ; LifeLines Cohort Study, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLifelines is a prospective population-based cohort study investigating the biological, behavioral and environmental determinants of healthy ageing among 167,729 participants from the North East region of the Netherlands. The collection and geocoding of (history of) home and work addresses allows linkage of individual-level health data to detailed exposure data. We describe the reasons for choosing particular assessments of environmental exposures in LifeLines and consider the implications for future investigations.

methodsExposure to ambient air pollution and road traffic noise was estimated using harmonized models. Data on noise annoyance, perceived exposure to electromagnetic fields, perceived living environment, and neighborhood characteristics were collected with questionnaires. A comprehensive medical assessment and questionnaires were completed in order to assess determinants of health and well-being. Blood and urine samples were collected from all participants and genome wide association data are available for a subsample of 15,638 participants.

resultsMean age was 45 years (standard deviation (SD) 13 years), and 59 % were female. Median levels of NO2 and PM10 were 15.7 (interquartile range (IQR) 4.9) μg/m(3) and 24.0 (IQR 0.6) μg/m(3) respectively. Median levels of daytime road traffic noise were 54.0 (IQR 4.2) dB(A).

conclusionsThe combination of harmonized environmental exposures and extensive assessment of health outcomes in LifeLines offers great opportunities for environmental epidemiology. LifeLines aims to be a resource for the international scientific community.

Indexed as

Chronic diseaseProspective cohort study, Environmental exposures, Harmonization

Identifiers

PMID27482379
PMCPMC4968004

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.