Evidence map›Paper›PMID 27482292›Full record

ArticleAnalytical methods : advancing methods and applications2016

A Label-free Sirtuin 1 Assay based on Droplet-Electrospray Ionization Mass Spectrometry.

Shuwen Sun, Benjamin C Buer, E Neil G Marsh, Robert T Kennedy

Abstract read
In one paragraph

Article in Analytical methods : advancing methods and applications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Droplet Microfluidics and Directed Evolution of Enzymes: An Intertwined Journey.Angewandte Chemie (International ed. in English) · 2021
    Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shuwen SunUniversity of Michigan, Department of Chemistry, Ann Arbor, Michigan, 48109, United States.
Benjamin C BuerUniversity of Michigan, Department of Chemistry, Ann Arbor, Michigan, 48109, United States.
E Neil G MarshUniversity of Michigan, Department of Chemistry, Ann Arbor, Michigan, 48109, United States; University of Michigan, Department of Biological Chemistry, Ann Arbor, Michigan, 48109, United States.
Robert T KennedyUniversity of Michigan, Department of Chemistry, Ann Arbor, Michigan, 48109, United States; University of Michigan, Department of Pharmacology, Ann Arbor, Michigan, 48109, United States.
Ann Arbor Center for Independent Living · USUniversity of Michigan–Ann Arbor · US

Funding

High throughput mass spectrometry and electrophoresis assay systemsR01GM102236 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KENNEDY, ROBERT T · 2012 to 2015
$1.1M
NIGMS NIH HHS R01 GM102236
6 · The paper itself

Abstract

Sirtuin 1(SIRT1) is a NAD

Indexed as

High Throughput ScreeningLabel-freeMass SpectrometrySirtuin 1

Identifiers

PMID27482292
PMCPMC4962873
OpenAlexW2325486812

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.