Evidence map›Paper›PMID 27482143›Full record

ArticleSynlett : accounts and rapid communications in synthetic organic chemistry

Stereoselective Synthesis of Trisubstituted Vinyl Bromides by Addition of Alkynes to Oxocarbenium Ions.

Andrew R Ehle, Melissa G Morris, Bryan D Klebon, Glenn P A Yap, Mary P Watson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synlett : accounts and rapid communications in synthetic organic chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Alkynyl Halo-Aza-Prins Annulative Couplings.The Journal of organic chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew R EhleDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Melissa G MorrisDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Bryan D KlebonDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Glenn P A YapDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
Mary P WatsonDepartment of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI SCHMITZ, KARL ROBERT · 2014 to 2024
$26.8M
Molecular Design of Advanced BiomaterialsP20GM103541 · NIGMS · UNIVERSITY OF DELAWARE · PI POLENOVA, TATYANA · 2012 to 2012
$2.1M
Q-Exactive Orbitrap LC-MC/MS SystemS10OD016267 · OD · UNIVERSITY OF DELAWARE · PI JOHNSTON, MURRAY V · 2013 to 2013
$573k
High Performance Digital NMR SpectrometerS10RR026962 · NCRR · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2010 to 2010
$500k
NCRR NIH HHS S10 RR026962NIGMS NIH HHS P20 GM103541NIGMS NIH HHS P20 GM104316NIH HHS S10 OD016267
6 · The paper itself

Abstract

We have developed an efficient method for the synthesis of (E)-trisubstituted vinyl bromides via a Friedel-Crafts-type addition of alkynes to oxocarbenium ions formed in situ from acetals. The success of this reaction relies on identification of MgBr

Indexed as

alkyneFriedel–Craftsoxocarbenium ionstereoselectivetrisubstituted vinyl bromidevinylation

Identifiers

PMID27482143
PMCPMC4961304

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.