ArticleProceedings of the National Academy of Sciences of the United States of America2016
Early gut colonizers shape parasite susceptibility and microbiota composition in honey bee workers.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.
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Who cites it
105 citing papers in PubMed.
- Wake Up and Smell the Infected Bees: Volatile Cues ofEcology and evolution · 2026Article
- Contrasting Toxicity Classes Differentially Affect Gut Microbiota Composition in Honey Bees.Insects · 2026Article
- Nanoplastic-induced microbiome shifts reduceISME communications · 2026Article
- Unintended consequences of antibiotic use in beekeeping: drone health as a potential vulnerability.Animal microbiome · 2025Article
- Holobiont-holobiont interactions across host-ectoparasite systems.Parasites & vectors · 2025Review
- Host-Microbiome Interactions as Moderators of Host Quality and Biodiversity-Disease Relationships.Integrative and comparative biology · 2025Review
- Antibiotic treatment of honey bee colonies alters early gut microbiome assembly and induces persistent dysbiosis in newly emerged workers.Scientific reports · 2025Article
- Microbial responses to antibiotics cryptically shift the direction of disease outcomes.Scientific reports · 2025Article
- Parasite-Induced Replacement of Host Microbiota: Impact of Xenos gadagkari Parasitization on the Microbiota of Polistes wattii.Microbial ecology · 2025Article
- Social organization and physical environment shape the microbiome of harvester ants.Animal microbiome · 2025Article
- Discovery of reproductive tissue-associated bacteria and the modes of microbiota acquisition in male honey bees (drones).mSphere · 2025Article
- The trypanosomatid (Kinetoplastida: Trypanosomatidae) parasites in bees: A review on their environmental circulation, impacts and implications.Current research in insect science · 2025Review
- Interaction with refuse piles is associated with co-occurrence of core gut microbiota in workers of the ant Aphaenogaster picea.Access microbiology · 2025Article
- What Veterinarians Need to Know About the Newly-Emerging Field of Insects-as-Food-and-Feed.Veterinary sciences · 2024Review
- A faster killing effect of plastid-mediated RNA interference on a leaf beetle through induced dysbiosis of the gut bacteria.Plant communications · 2024Article
- Exploring the interactions between Nosema ceranae infection and the honey bee gut microbiome.Scientific reports · 2024Article
- Review
- Prospects of probiotics in beekeeping: a review for sustainable approach to boost honeybee health.Archives of microbiology · 2024Review
- Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages.mSystems · 2024Article
- A longitudinal field study of commercial honey bees shows that non-native probiotics do not rescue antibiotic treatment, and are generally not beneficial.Scientific reports · 2024Article
45 more citing papers are in PubMed but not listed here.
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Microbial symbionts living within animal guts are largely composed of resident bacterial species, forming communities that often provide benefits to the host. Gut microbiomes of adult honey bees (Apis mellifera) include core residents such as the betaproteobacterium Snodgrassella alvi, alongside transient parasites such as the protozoan Lotmaria passim To test how these species affect microbiome composition and host physiology, we administered S alvi and/or L passim inocula to newly emerged worker bees from four genetic backgrounds (GH) and reared them in normal (within hives) or stressed (protein-deficient, asocial) conditions. Microbiota acquired by normal bees were abundant but quantitatively differed across treatments, indicating treatment-associated dysbiosis. Pretreatment with S. alvi made normal bees more susceptible to L. passim and altered developmental and detoxification gene expression. Stressed bees were more susceptible to L. passim and were depauperate in core microbiota, yet supplementation with S. alvi did not alter this susceptibility. Microbiomes were generally more variable by GH in stressed bees, which also showed opposing and comparatively reduced modulation of gene expression responses to treatments compared with normal bees. These data provide experimental support for a link between altered gut microbiota and increased parasite and pathogen prevalence, as observed from honey bee colony collapse disorder.
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